RPRD2

Description		regulation of nuclear pre-mRNA domain containing 2
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GO Annotations	Cellular Component	Nucleoplasm Transcription Preinitiation Complex
	Molecular Function	RNA Polymerase II Complex Binding RNA Polymerase II C-terminal Domain Binding
	Biological Process	MRNA 3'-end Processing
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Bitter non-alcoholic beverage consumption ( 31046077) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Broad depression or bipolar disorder ( 30626913) Caffeine consumption from tea ( 33287642) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Lung function (FEV1) ( 30175238) Neutrophil count ( 32888494) Refractive error ( 32231278) Schizophrenia ( 28991256) Spontaneous coronary artery dissection ( 32887874) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Novel Interacting Genes		9 novel interacting genes: CSNK2A1 CTDSP1 MTNR1B PLEKHO1 PPP1CA PPP1CC SPOP UPF1 VPS45
Interacting Genes		9 interacting genes: CSNK2A1 CTDSP1 MTNR1B PLEKHO1 PPP1CA PPP1CC SPOP UPF1 VPS45
Entrez ID		23248
HPRD ID		11084
Ensembl ID		ENSG00000163125
Uniprot IDs		Q5VT52
PDB IDs		4FLB
Enriched GO Terms of Interacting Partners?		Protein Dephosphorylation Phosphatase Activity PTW/PP1 Phosphatase Complex Protein Serine/threonine Phosphatase Activity Regulation Of Circadian Rhythm Dephosphorylation Phosphoprotein Phosphatase Activity Protein Phosphatase 1 Binding Photoperiodism Entrainment Of Circadian Clock By Photoperiod Entrainment Of Circadian Clock Chromosome, Telomeric Region Rhythmic Process Double-strand Break Repair Via Nonhomologous End Joining Glycogen Metabolic Process Circadian Regulation Of Gene Expression Energy Reserve Metabolic Process Protein-containing Complex Binding Chromosome Organization Polysaccharide Metabolic Process Regulation Of Translation RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Regulation Of Translational Initiation Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body DNA Repair Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Melatonin Receptor Activity Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Telomere Maintenance Positive Regulation Of Termination Of DNA-templated Transcription Positive Regulation Of Termination Of RNA Polymerase II Transcription Regulation Of Protein-containing Complex Disassembly Telomere Organization Circadian Rhythm Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Double-stranded DNA Helicase Activity Supraspliceosomal Complex Positive Regulation Of MRNA Cis Splicing, Via Spliceosome Muscle Cell Projection Membrane Positive Regulation Of Aggrephagy Regulation Of Neuronal Action Potential Dendritic Spine Post-transcriptional Regulation Of Gene Expression Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Transmission Of Nerve Impulse Glycogen Granule Positive Regulation Of Transmission Of Nerve Impulse
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