NUP210

Description		nucleoporin 210
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Nuclear Membrane
	Molecular Function	Protein Binding
	Biological Process	Nucleocytoplasmic Transport Protein Transport MRNA Transport
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS		Coronary artery disease in type 1 diabetes ( 29695241)
Novel Interacting Genes		8 novel interacting genes: ADGRG2 CDK1 EXOSC5 HDAC11 MTDH TMEM40 TRIP6 TSEN2
Interacting Genes		8 interacting genes: ADGRG2 CDK1 EXOSC5 HDAC11 MTDH TMEM40 TRIP6 TSEN2
Entrez ID		23225
HPRD ID		06368
Ensembl ID		ENSG00000132182
Uniprot IDs		Q8TEM1
PDB IDs		7R5J 7R5K
Enriched GO Terms of Interacting Partners?
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