ZC3H4

Description		zinc finger CCCH-type containing 4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytosol
	Molecular Function	Chromatin Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Promoter-specific Chromatin Binding
	Biological Process	DNA-templated Transcription Termination Negative Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of DNA-templated Transcription Nuclear RNA Surveillance LncRNA Catabolic Process Negative Regulation Of LncRNA Transcription
Pathways		Nuclear RNA decay
Drugs
Diseases
GWAS		Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) BMI in smokers ( 28443625) Body fat distribution (arm fat ratio) ( 30664634) Body mass index ( 20935630 25673413 26961502 28552196 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Coffee consumption ( 31046077) HDL cholesterol levels ( 32203549) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) High density lipoprotein cholesterol levels ( 29083408) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference ( 25673412) Immature fraction of reticulocytes ( 32888494) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Metabolic syndrome ( 31589552) Obesity-related traits ( 23251661) Red blood cell count ( 27863252 32888494) Type 2 diabetes ( 30297969) Type 2 diabetes (time to event) ( 32589924) Waist circumference ( 25673412)
Novel Interacting Genes		2 novel interacting genes: POLR2A RNF10
Interacting Genes		2 interacting genes: POLR2A RNF10
Entrez ID		23211
HPRD ID		19314
Ensembl ID		ENSG00000130749
Uniprot IDs		Q9UPT8
PDB IDs		2CQE
Enriched GO Terms of Interacting Partners?		RNA-directed RNA Polymerase Activity Microfibril Binding RNA-templated Transcription Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane 5'-3' RNA Polymerase Activity Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Schwann Cell Proliferation RNA Polymerase II, Core Complex DNA-templated Transcription Termination Prp19 Complex Positive Regulation Of Myelination Negative Regulation Of Glial Cell Proliferation DNA-directed RNA Polymerase Activity Positive Regulation Of RNA Splicing MRNA Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II DNA-directed RNA Polymerase Complex Regulation Of Glial Cell Proliferation Negative Regulation Of Gliogenesis Postsynaptic Signal Transduction Regulation Of Myelination DNA-templated Transcription Elongation Protein Monoubiquitination MRNA Transcription Promoter-specific Chromatin Binding Protein Autoubiquitination Transferase Activity Nucleotidyltransferase Activity Kinase Binding Regulation Of Gliogenesis Cytosolic Ribosome Zinc Ion Binding
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