LPIN1

Description		lipin 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Nuclear Membrane
	Molecular Function	Transcription Coactivator Activity Protein Binding Phosphatidate Phosphatase Activity Hydrolase Activity
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Triglyceride Mobilization Mitotic Nuclear Membrane Disassembly Fatty Acid Catabolic Process Triglyceride Biosynthetic Process Animal Organ Regeneration Negative Regulation Of Myelination Cellular Response To Insulin Stimulus Positive Regulation Of Transcription By RNA Polymerase II Phosphatidylethanolamine Metabolic Process Phosphatidic Acid Metabolic Process Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of Phosphatidic Acid Biosynthetic Process
Pathways		Synthesis of PC Synthesis of PE Depolymerization of the Nuclear Lamina Triglyceride biosynthesis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS		Chronotype ( 30696823) Metabolite levels ( 23823483) Post bronchodilator percent predicted FEV1 in smoking ( 30068317) Severe insulin-resistant type 2 diabetes ( 34737425)
Novel Interacting Genes		2 novel interacting genes: CDK6 RRM2
Interacting Genes		2 interacting genes: CDK6 RRM2
Entrez ID		23175
HPRD ID		09271
Ensembl ID		ENSG00000134324
Uniprot IDs		Q14693
PDB IDs
Enriched GO Terms of Interacting Partners?		Cyclin D3-CDK6 Complex Regulation Of Mitotic Cell Cycle Phase Transition Cyclin D1-CDK6 Complex Cyclin D2-CDK6 Complex FBXO Family Protein Binding Ribonucleoside-diphosphate Reductase Activity, Thioredoxin Disulfide As Acceptor Ribonucleoside-diphosphate Reductase Complex Gliogenesis Negative Regulation Of Monocyte Differentiation Cell Dedifferentiation Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Ferric Iron Binding Lateral Ventricle Development Regulation Of Cell Cycle Process Type B Pancreatic Cell Development Regulation Of Hematopoietic Stem Cell Differentiation Deoxyribonucleotide Biosynthetic Process Protein Heterotetramerization 2'-deoxyribonucleotide Biosynthetic Process Astrocyte Development Regulation Of Monocyte Differentiation Generation Of Neurons Hematopoietic Stem Cell Differentiation Negative Regulation Of Cellular Senescence Dentate Gyrus Development Protein Heterooligomerization Cyclin-dependent Protein Serine/threonine Kinase Activity Blastocyst Development Cyclin Binding Regulation Of Cell Cycle T Cell Differentiation In Thymus Regulation Of Hematopoietic Progenitor Cell Differentiation Cyclin-dependent Protein Kinase Holoenzyme Complex Deoxyribonucleotide Metabolic Process Regulation Of Cellular Senescence Regulation Of Erythrocyte Differentiation Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Fibroblast Proliferation Positive Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Osteoblast Differentiation Glial Cell Development Regulation Of Stem Cell Differentiation Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Nucleoside Diphosphate Metabolic Process Ribonucleoside Diphosphate Metabolic Process Regulation Of Fibroblast Proliferation
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