SIPA1L3

Description		signal induced proliferation associated 1 like 3
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Extracellular Space Nucleoplasm Cytoplasm Golgi Apparatus Plasma Membrane Membrane Apical Plasma Membrane Apical Part Of Cell Tricellular Tight Junction Glutamatergic Synapse Postsynaptic Specialization, Intracellular Component
	Molecular Function	GTPase Activator Activity Protein Binding
	Biological Process	Eye Development Hematopoietic Progenitor Cell Differentiation Epithelial Cell Morphogenesis Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Establishment Of Epithelial Cell Polarity
Pathways
Drugs
Diseases
GWAS		Chronic kidney disease ( 29124443) Cognitive performance (processing speed) ( 31598132) Creatinine levels ( 29124443) Estimated glomerular filtration rate ( 29124443 31015462 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate (creatinine) ( 26831199 28452372) Gut microbiota (bacterial taxa) ( 27723756) Hyperuricemia ( 29124443) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Serum uric acid levels ( 29124443)
Novel Interacting Genes		2 novel interacting genes: GRIK1 SRPK2
Interacting Genes		2 interacting genes: GRIK1 SRPK2
Entrez ID		23094
HPRD ID		18755
Ensembl ID		ENSG00000105738
Uniprot IDs		B2RWP0 O60292
PDB IDs
Enriched GO Terms of Interacting Partners?		Glutamate-gated Calcium Ion Channel Activity Glutamate-gated Receptor Activity Kainate Selective Glutamate Receptor Complex Kainate Selective Glutamate Receptor Activity R-loop Processing Nuclear Speck Organization Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Ligand-gated Monoatomic Ion Channel Activity Ligand-gated Ion Channel Signaling Pathway Intracellular Signaling Cassette Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential Peptidyl-serine Phosphorylation 14-3-3 Protein Binding Nuclear Body Organization Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Positive Regulation Of Viral Genome Replication Glutamate Receptor Signaling Pathway
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