EXPH5

Description		exophilin 5
Image		No pdb structure
GO Annotations	Cellular Component	Endosome
	Molecular Function	Small GTPase Binding
	Biological Process	Keratinocyte Development Intracellular Protein Transport Positive Regulation Of Exocytosis Positive Regulation Of Protein Secretion Multivesicular Body Sorting Pathway
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33339817) Lymphocyte count ( 27863252) Nonunion in individuals with fractures ( 30680360) Plateletcrit ( 32888494) Refractive error ( 32231278)
Novel Interacting Genes		3 novel interacting genes: APC RAB27A SMAD9
Interacting Genes		3 interacting genes: APC RAB27A SMAD9
Entrez ID		23086
HPRD ID		08341
Ensembl ID		ENSG00000110723
Uniprot IDs		B4E1U8 B4E2C3 Q149M6 Q8NEV8
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytotoxic T Cell Degranulation Positive Regulation Of Constitutive Secretory Pathway Wnt Signalosome Leading Edge Membrane Positive Regulation Of Pseudopodium Assembly Negative Regulation Of Microtubule Depolymerization Regulation Of Attachment Of Spindle Microtubules To Kinetochore Enzyme-linked Receptor Protein Signaling Pathway Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mitotic Spindle Assembly Checkpoint Signaling Protein Kinase Regulator Activity Heart Valve Development Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Mitotic Metaphase/anaphase Transition Beta-catenin Destruction Complex Negative Regulation Of Cyclin-dependent Protein Kinase Activity Catenin Complex Cellular Developmental Process Dynein Complex Binding Negative Regulation Of Protein Serine/threonine Kinase Activity Endocardial Cushion Morphogenesis Gamma-catenin Binding Microtubule Plus-end Binding Plasma Membrane Bounded Cell Projection Positive Regulation Of Protein Localization To Centrosome Regulation Of Protein Localization To Centrosome Heteromeric SMAD Protein Complex SMAD Protein Complex SMAD Protein Signal Transduction I-SMAD Binding Cellular Response To BMP Stimulus Exosomal Secretion Pigment Granule Localization Establishment Of Melanosome Localization Multivesicular Body Membrane Complement-dependent Cytotoxicity Multivesicular Body Organization Pigment Cell Differentiation Melanosome Membrane Melanosome Localization Weibel-Palade Body Exocytic Vesicle Natural Killer Cell Degranulation Myosin V Binding Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Melanosome Transport Melanocyte Differentiation Pigment Granule Transport Positive Regulation Of Macromolecule Metabolic Process Synaptic Vesicle Transport
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