MON2

Description		MON2 regulator of endosome-to-Golgi trafficking
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Membrane Early Endosome Membrane Extracellular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Golgi To Endosome Transport Protein Transport
Pathways
Drugs
Diseases
GWAS		Pyoderma gangrenosum in inflammatory bowel disease ( 24487271) Triglyceride levels ( 32203549) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Novel Interacting Genes		1 novel interacting genes: MTNR1B
Interacting Genes		1 interacting genes: MTNR1B
Entrez ID		23041
HPRD ID		11123
Ensembl ID		ENSG00000061987
Uniprot IDs		A0A286YFF8 B7ZM73 Q7Z3U7
PDB IDs
Enriched GO Terms of Interacting Partners?		Melatonin Receptor Activity Positive Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Neuronal Action Potential Negative Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Vasoconstriction Regulation Of CGMP-mediated Signaling Positive Regulation Of Circadian Rhythm Negative Regulation Of Nervous System Process Regulation Of Transmission Of Nerve Impulse Negative Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Circadian Sleep/wake Cycle Positive Regulation Of Behavior Negative Regulation Of Insulin Secretion Negative Regulation Of Peptide Secretion G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Regulation Of Action Potential Regulation Of Vasoconstriction Negative Regulation Of Hormone Secretion Negative Regulation Of Protein Secretion Regulation Of Behavior Camera-type Eye Development Regulation Of Circadian Rhythm Eye Development Negative Regulation Of Protein Transport Regulation Of Nervous System Process Negative Regulation Of Establishment Of Protein Localization Blood Vessel Diameter Maintenance Negative Regulation Of Secretion By Cell Regulation Of Tube Size Regulation Of Insulin Secretion Negative Regulation Of Secretion Sensory Organ Development Negative Regulation Of Neuron Apoptotic Process Carbohydrate Homeostasis Regulation Of Peptide Hormone Secretion Glucose Homeostasis Negative Regulation Of Protein Localization Regulation Of Blood Circulation Regulation Of Hormone Secretion Regulation Of Protein Secretion Vascular Process In Circulatory System Regulation Of Neuron Apoptotic Process Chemical Synaptic Transmission Circulatory System Process Trans-synaptic Signaling
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