MYT1L

Description		myelin transcription factor 1 like
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Chromosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity Zinc Ion Binding Retinoic Acid-responsive Element Binding Metal Ion Binding Cobalt Ion Binding Metal Ion Sequestering Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nervous System Development Cell Differentiation Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Commitment Neuron Fate Specification Neuron Development
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Attention deficit hyperactivity disorder ( 18839057) Caudate nucleus volume ( 31530798) Cognitive decline rate in late mild cognitive impairment ( 26252872) Diabetic retinopathy ( 21441570) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Glucose homeostasis traits ( 25524916) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota (functional units) ( 27694959) Impulsivity ( 30718321) Impulsivity (motor) ( 30718321) Impulsivity (non-planning) ( 30718321) Inflammatory skin disease ( 25574825) Mitochondrial DNA copy number (white blood cells) ( 30704525) Moderate-to-late spontaneous preterm birth ( 31194736) Response to selective serotonin reuptake inhibitors and depression ( 27622933) Systemic sclerosis ( 30247649) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Type 2 diabetes (age of onset) ( 28060188) Vitamin B levels in ischemic stroke ( 25147783)
Novel Interacting Genes		6 novel interacting genes: AURKA CDC5L DISC1 DYRK1A PCNT TGFBR1
Interacting Genes		6 interacting genes: AURKA CDC5L DISC1 DYRK1A PCNT TGFBR1
Entrez ID		23040
HPRD ID		14797
Ensembl ID		ENSG00000186487
Uniprot IDs		A0A2R8YF72 A0A3B3IRM3 A0A3B3IRX5 A0A3B3IS14 A0A3B3IS61 A0A3B3ISW5 Q9UL68
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule Microtubule Organizing Center Protein Serine/threonine/tyrosine Kinase Activity Centrosome Protein Localization To Centrosome Plasma Membrane Bounded Cell Projection Organization Cilium Organization Peptidyl-serine Phosphorylation Protein Localization To Cytoskeleton Protein Phosphorylation Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Phosphorylation Cell Projection Organization Protein Serine/threonine Kinase Activity Histone H3T45 Kinase Activity Microtubule Cytoskeleton Organization Mitotic Spindle Organization Protein Kinase Activity Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Autophosphorylation Nervous System Development Regulation Of Signal Transduction By P53 Class Mediator Cytoskeleton Vascular Endothelial Cell Proliferation Epicardium Morphogenesis Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Kinase Activity Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Oocyte Maturation Proepicardium Development Angiogenesis Involved In Coronary Vascular Morphogenesis Transforming Growth Factor Beta Ligand-receptor Complex Pyramidal Neuron Migration To Cerebral Cortex Central Region Of Growth Cone Centriole Spindle Organization Organelle Assembly Spindle Assembly Involved In Female Meiosis I Germinal Vesicle Histone H3S10 Kinase Activity Positive Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Positive Regulation Of Tight Junction Disassembly Positive Regulation Of Cell Growth Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Metabolic Process WD40-repeat Domain Binding Negative Regulation Of Heterochromatin Formation
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