MMRN1

Description		multimerin 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix Platelet Alpha Granule Platelet Alpha Granule Lumen Multimerin Complex
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding
	Biological Process	Cell Adhesion Blood Coagulation Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Adhesion Mediated By Integrin Negative Regulation Of Wound Healing Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Platelet Aggregation
Pathways		Platelet degranulation O-linked glycosylation
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Bitter alcoholic beverage consumption ( 31046077) Parkinson's disease ( 19915575)
Novel Interacting Genes		3 novel interacting genes: CDKN2A F5 SNCA
Interacting Genes		3 interacting genes: CDKN2A F5 SNCA
Entrez ID		22915
HPRD ID		03267
Ensembl ID		ENSG00000138722
Uniprot IDs		E7EPG1 Q13201
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid Fibril Formation Protein Destabilization Copper Ion Binding Ligase Inhibitor Activity Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Cellular Response To Chemical Stress Negative Regulation Of Protein Neddylation Ubiquitin-protein Transferase Inhibitor Activity Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Cellular Response To Oxidative Stress Senescence-associated Heterochromatin Focus Negative Regulation Of Immature T Cell Proliferation In Thymus Apoptotic Process Involved In Mammary Gland Involution Response To Vitamin K Negative Regulation Of Dopamine Metabolic Process Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Chaperone-mediated Autophagy Regulation Of Serotonin Uptake Negative Regulation Of Immature T Cell Proliferation Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Ubiquitin Protein Ligase Activity Mitochondrial Depolarization Oncogene-induced Cell Senescence Regulation Of Protein Stability Positive Regulation Of Apoptotic Process Involved In Development Somatic Stem Cell Division Protein Localization To Nucleolus Negative Regulation Of Cyclin-dependent Protein Kinase Activity Positive Regulation Of Apoptotic Process Involved In Morphogenesis Regulation Of Membrane Potential Negative Regulation Of Catabolic Process Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of T Cell Differentiation In Thymus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Localization Response To Oxidative Stress Mitochondrial Matrix
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