ATF5

Description		activating transcription factor 5
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Centrosome Cytosol Cytoskeleton RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Tubulin Binding Kinase Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Circadian Rhythm Negative Regulation Of Cell Population Proliferation Post-embryonic Development Regulation Of Gene Expression Olfactory Bulb Interneuron Differentiation Olfactory Bulb Interneuron Development Cerebellar Granule Cell Precursor Proliferation Olfactory Lobe Development Multicellular Organism Growth Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Fat Cell Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Centrosome Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition
Pathways		Response of EIF2AK1 (HRI) to heme deficiency Mitochondrial unfolded protein response (UPRmt) Mitochondrial unfolded protein response (UPRmt)
Drugs		Pseudoephedrine
Diseases
GWAS
Novel Interacting Genes		18 novel interacting genes: ATXN1 CCDC6 CCND3 CDC34 CEBPA CEBPE CEBPG DISC1 EIF2B1 EP300 FBXO7 GABBR1 GABBR2 GIT2 GPS2 KEAP1 SYCE1L TTR
Interacting Genes		18 interacting genes: ATXN1 CCDC6 CCND3 CDC34 CEBPA CEBPE CEBPG DISC1 EIF2B1 EP300 FBXO7 GABBR1 GABBR2 GIT2 GPS2 KEAP1 SYCE1L TTR
Entrez ID		22809
HPRD ID		05906
Ensembl ID		ENSG00000169136
Uniprot IDs		Q9Y2D1
PDB IDs
Enriched GO Terms of Interacting Partners?		Mononuclear Cell Differentiation G Protein-coupled GABA Receptor Activity G Protein-coupled GABA Receptor Complex G Protein-coupled Receptor Heterodimeric Complex Leukocyte Differentiation GABA Receptor Complex Integrated Stress Response Signaling Neuron-glial Cell Signaling GABA Receptor Activity Identical Protein Binding STAT Family Protein Binding DNA-templated Transcription Lymphocyte Activation Protein-containing Complex Myeloid Cell Differentiation Lymphocyte Differentiation Protein K48-linked Ubiquitination Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Leukocyte Activation Signal Transduction B Cell Differentiation Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Proteolysis Involved In Protein Catabolic Process RNA Polymerase II Transcription Regulator Complex Gamma-aminobutyric Acid Signaling Pathway Protein Heterodimerization Activity Granulocyte Differentiation Protein-containing Complex Binding Cell Activation Synaptic Transmission, GABAergic Nucleoplasm Regulation Of Cell Differentiation Macrophage Differentiation Regulation Of Ubiquitin-dependent Protein Catabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Binding RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding B Cell Activation Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite
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