VEGFD

Description		vascular endothelial growth factor D
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane Platelet Alpha Granule Lumen
	Molecular Function	Platelet-derived Growth Factor Receptor Binding Vascular Endothelial Growth Factor Receptor Binding Protein Binding Growth Factor Activity Chemoattractant Activity Identical Protein Binding Vascular Endothelial Growth Factor Receptor 3 Binding Receptor Ligand Activity
	Biological Process	Angiogenesis Response To Hypoxia Sprouting Angiogenesis Positive Regulation Of Cell Population Proliferation Response To Bacterium Cell Differentiation Vascular Endothelial Growth Factor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Fibroblast Proliferation Positive Chemotaxis Induction Of Positive Chemotaxis Positive Regulation Of Cell Division Positive Regulation Of Mast Cell Chemotaxis Dopaminergic Neuron Differentiation
Pathways		Platelet degranulation VEGF ligand-receptor interactions VEGF binds to VEGFR leading to receptor dimerization
Drugs
Diseases		Gastric cancer
GWAS
Novel Interacting Genes		4 novel interacting genes: FLT4 ITGA9 KDR VAMP3
Interacting Genes		4 interacting genes: FLT4 ITGA9 KDR VAMP3
Entrez ID		2277
HPRD ID		02102
Ensembl ID		ENSG00000165197
Uniprot IDs		O43915
PDB IDs		2XV7
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Activity Lymph Vessel Development Vascular Endothelial Growth Factor Signaling Pathway Cellular Response To Vascular Endothelial Growth Factor Stimulus Vascular Endothelial Growth Factor Receptor Signaling Pathway Growth Factor Binding Transmembrane Receptor Protein Tyrosine Kinase Activity Peptidyl-tyrosine Phosphorylation Lung Alveolus Development Vasculature Development Positive Regulation Of Endothelial Cell Proliferation Cell Surface Positive Regulation Of Nitric Oxide-cGMP Mediated Signal Transduction Protein Autophosphorylation Positive Regulation Of Endothelial Cell Migration Protein Tyrosine Kinase Activity Regulation Of Endothelial Cell Proliferation Integrin Alpha9-beta1 Complex Cell-substrate Adhesion Cell Migration Regulation Of Multicellular Organismal Process Regulation Of Endothelial Cell Migration Positive Regulation Of Epithelial Cell Proliferation Receptor Complex Positive Regulation Of ERK1 And ERK2 Cascade Cell Motility Response To Hydrogen Sulfide Cellular Response To Hydrogen Sulfide Post-embryonic Camera-type Eye Morphogenesis Vascular Endothelial Growth Factor Binding Positive Regulation Of Protein Phosphorylation Integrin Binding Involved In Cell-matrix Adhesion Positive Regulation Of Nitric Oxide Mediated Signal Transduction Endocardium Development Positive Regulation Of Phosphorylation Cellular Response To Growth Factor Stimulus Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of CGMP-mediated Signaling Blood Vessel Endothelial Cell Differentiation Sorting Endosome Post-embryonic Eye Morphogenesis Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Regulation Of Histamine Secretion By Mast Cell Tube Morphogenesis Angiogenesis Positive Regulation Of Phosphate Metabolic Process Response To Growth Factor Early Endosome Vascular Wound Healing Positive Regulation Of Mitochondrial Depolarization
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