NAPEPLD

Description		N-acyl phosphatidylethanolamine phospholipase D
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GO Annotations	Cellular Component	Golgi Membrane Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Endosome Early Endosome Golgi Apparatus Membrane Smooth Endoplasmic Reticulum Membrane Early Endosome Membrane Photoreceptor Outer Segment Membrane Presynaptic Membrane Neuron Projection Neuronal Cell Body Postsynaptic Membrane Extracellular Exosome Hippocampal Mossy Fiber To CA3 Synapse Presynapse
	Molecular Function	Phospholipase Activity Zinc Ion Binding Hydrolase Activity Bile Acid Binding Identical Protein Binding Metal Ion Binding N-acylphosphatidylethanolamine-specific Phospholipase D Activity
	Biological Process	Temperature Homeostasis Lipid Metabolic Process Phospholipid Metabolic Process Phospholipid Catabolic Process Lipid Catabolic Process Response To Isolation Stress Host-mediated Modulation Of Intestinal Microbiota Composition Positive Regulation Of Inflammatory Response N-acylethanolamine Metabolic Process N-acylphosphatidylethanolamine Metabolic Process Positive Regulation Of Brown Fat Cell Differentiation Negative Regulation Of Eating Behavior
Pathways		Biosynthesis of A2E, implicated in retinal degradation
Drugs		Medical Cannabis
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: PPP1CC
Interacting Genes		1 interacting genes: PPP1CC
Entrez ID		222236
HPRD ID		14809
Ensembl ID		ENSG00000161048
Uniprot IDs		Q6IQ20
PDB IDs		4QN9 8P90 8P96 8PC4
Enriched GO Terms of Interacting Partners?		Protein Phosphatase 1 Binding Photoperiodism Entrainment Of Circadian Clock By Photoperiod Blastocyst Development Positive Regulation Of Glial Cell Proliferation PTW/PP1 Phosphatase Complex Entrainment Of Circadian Clock Lamin Binding Regulation Of Glial Cell Proliferation Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Circadian Regulation Of Gene Expression Glycogen Metabolic Process Energy Reserve Metabolic Process Positive Regulation Of Gliogenesis Polysaccharide Metabolic Process Nuclear Chromosome Segregation Cleavage Furrow Phosphatase Activity Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity Microtubule Organizing Center Protein Phosphatase Binding Regulation Of Gliogenesis Regulation Of Circadian Rhythm Regulation Of Nucleocytoplasmic Transport Chromosome Segregation Dephosphorylation Phosphoprotein Phosphatase Activity Circadian Rhythm Dendritic Spine Chromosome, Centromeric Region Kinetochore Chromosome, Telomeric Region Midbody Energy Derivation By Oxidation Of Organic Compounds Mitochondrial Outer Membrane Protein Domain Specific Binding Presynapse Positive Regulation Of Neurogenesis Postsynapse MAPK Cascade Rhythmic Process Positive Regulation Of Nervous System Development Regulation Of Intracellular Transport
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