NT5DC1

Description		5'-nucleotidase domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Protein Binding 5'-nucleotidase Activity Hydrolase Activity Metal Ion Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Adolescent idiopathic scoliosis ( 31417091) Dental caries ( 23064961) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) HDL cholesterol levels ( 30698716) Hematocrit ( 32888494) High density lipoprotein cholesterol levels ( 33339817) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Myopia ( 27182965) Refractive error ( 32231278) Serum alkaline phosphatase levels ( 33547301)
Novel Interacting Genes		1 novel interacting genes: OGT
Interacting Genes		1 interacting genes: OGT
Entrez ID		221294
HPRD ID		14845
Ensembl ID		ENSG00000178425
Uniprot IDs		Q5TFE4 Q9H2R1
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Regulation Of Transcription By Glucose NSL Complex Acetylglucosaminyltransferase Activity Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Sin3-type Complex Histone Acetyltransferase Complex Negative Regulation Of Stem Cell Population Maintenance Regulation Of Protein Localization To Synapse Regulation Of Receptor Localization To Synapse Mitophagy Protein Localization To Lysosome Circadian Regulation Of Gene Expression Positive Regulation Of Stem Cell Population Maintenance Cellular Response To Glucose Stimulus Regulation Of Stem Cell Population Maintenance Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Carbohydrate Catabolic Process Regulation Of Gluconeogenesis Regulation Of ATP Metabolic Process Regulation Of Glycolytic Process Positive Regulation Of TORC1 Signaling Cellular Response To Carbohydrate Stimulus Regulation Of Necroptotic Process Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Protein Catabolic Process Phosphatidylinositol-3,4,5-trisphosphate Binding Pyroptotic Inflammatory Response Cellular Response To Nutrient Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Autophagy Of Mitochondrion Positive Regulation Of Translational Initiation Regulation Of Rac Protein Signal Transduction Negative Regulation Of Protein Ubiquitination TORC1 Signaling Regulation Of Insulin Receptor Signaling Pathway Regulation Of Programmed Necrotic Cell Death Positive Regulation Of TOR Signaling Chromatin DNA Binding Intracellular Glucose Homeostasis TOR Signaling Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Purine Nucleotide Metabolic Process
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