RASGEF1A

Description		RasGEF domain family member 1A
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Small GTPase-mediated Signal Transduction Ras Protein Signal Transduction Cell Migration Positive Regulation Of Ras Protein Signal Transduction
Pathways		RAF/MAP kinase cascade
Drugs
Diseases
GWAS		Asthma ( 32296059) Blood urea nitrogen levels ( 29403010) Hirschsprung disease ( 19196962 25310821) Multiple sclerosis ( 31604244) Obesity-related traits ( 23251661) Recurrent major depressive disorder ( 29317602) Telomere length ( 24478790)
Novel Interacting Genes		1 novel interacting genes: NEDD4
Interacting Genes		1 interacting genes: NEDD4
Entrez ID		221002
HPRD ID		15211
Ensembl ID		ENSG00000198915
Uniprot IDs		Q8N9B8
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Channel Inhibitor Activity Phosphoserine Residue Binding Nuclear Receptor-mediated Corticosteroid Signaling Pathway Beta-2 Adrenergic Receptor Binding Phosphothreonine Residue Binding Negative Regulation Of Potassium Ion Export Across Plasma Membrane Formation Of Structure Involved In A Symbiotic Process Sodium Channel Inhibitor Activity Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Potassium Ion Export Across Plasma Membrane Progesterone Receptor Signaling Pathway Potassium Channel Inhibitor Activity Endocardial Cushion Development Negative Regulation Of Sodium Ion Transport Proline-rich Region Binding Receptor Catabolic Process RNA Polymerase Binding Negative Regulation Of Potassium Ion Transmembrane Transport Apicolateral Plasma Membrane Postsynaptic Cytosol Ionotropic Glutamate Receptor Binding Protein Targeting To Lysosome Viral Budding Negative Regulation Of Potassium Ion Transport Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Neuromuscular Junction Development Receptor Metabolic Process Protein Localization To Lysosome Receptor Internalization Regulation Of Dendrite Morphogenesis Establishment Of Protein Localization To Vacuole Negative Regulation Of Cation Transmembrane Transport Mesenchyme Development Regulation Of Potassium Ion Transmembrane Transport Outflow Tract Morphogenesis Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Nucleocytoplasmic Transport Protein K63-linked Ubiquitination Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Regulation Of Sodium Ion Transport Protein Targeting To Vacuole Negative Regulation Of Monoatomic Ion Transmembrane Transport Protein Monoubiquitination Regulation Of Potassium Ion Transport Cellular Response To UV Protein Localization To Vacuole Blood Vessel Morphogenesis Nuclear Receptor-mediated Signaling Pathway
Tagcloud ?