ABCB7

Description		ATP binding cassette subfamily B member 7
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Heme Transmembrane Transporter Activity ATP Hydrolysis Activity ATPase-coupled Transmembrane Transporter Activity Identical Protein Binding Protein Homodimerization Activity ABC-type Transporter Activity ABC-type Iron-sulfur Cluster Transporter Activity
	Biological Process	Intracellular Iron Ion Homeostasis Heme Transport Iron-sulfur Cluster Assembly Iron Ion Transmembrane Transport Transmembrane Transport Positive Regulation Of Heme Biosynthetic Process Iron-sulfur Cluster Export From The Mitochondrion Positive Regulation Of Iron-sulfur Cluster Assembly Negative Regulation Of Reactive Oxygen Species Biosynthetic Process
Pathways		Mitochondrial ABC transporters Cytosolic iron-sulfur cluster assembly
Drugs
Diseases		Sideroblastic anemia, including: Pyridoxine-refractory autosomal recessive sideroblastic anemia (PRARSA); X-linked sideroblastic anemia (XLSA); X-linked sideroblastic anemia with ataxia (ASAT)
GWAS		Metabolite levels ( 23823483)
Novel Interacting Genes		4 novel interacting genes: APP FECH RAP1GDS1 UBC
Interacting Genes		4 interacting genes: APP FECH RAP1GDS1 UBC
Entrez ID		22
HPRD ID		02137
Ensembl ID		ENSG00000131269
Uniprot IDs		A0A087WW65 A0A0S2Z2Z3 O75027
PDB IDs		7VGF
Enriched GO Terms of Interacting Partners?		Response To Lead Ion Monoatomic Ion Homeostasis Inorganic Ion Homeostasis Monoatomic Cation Homeostasis Mitochondrion Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Detection Of UV Ferrochelatase Activity CAAX-box Protein Maturation Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Chemical Homeostasis Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Tetrapyrrole Binding Iron-responsive Element Binding Regulation Of ERK5 Cascade Angiotensin-activated Signaling Pathway Involved In Heart Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Response To Platinum Ion Myosin Filament Assembly Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Response To Methylmercury Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Axon Choice Point Recognition Homeostatic Process
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