F2RL2

Description		coagulation factor II thrombin receptor like 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Apical Plasma Membrane Protein-containing Complex
	Molecular Function	Proteinase-activated Receptor Activity Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity G Protein-coupled Receptor Activity Protein Binding Thrombin-activated Receptor Activity Receptor Ligand Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Blood Coagulation Hemostasis Response To Wounding Platelet Activation Positive Regulation Of Insulin Secretion Regulation Of Biological Quality Thrombin-activated Receptor Signaling Pathway Ligand-gated Ion Channel Signaling Pathway
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs)
Drugs
Diseases
GWAS		Mean platelet volume ( 28031487) Phenylephrine infusion rate during anesthesia ( 31455332)
Novel Interacting Genes		9 novel interacting genes: AMT CDH5 CTSG ECT2 F11R F2 F2RL3 JAM2 JAM3
Interacting Genes		9 interacting genes: AMT CDH5 CTSG ECT2 F11R F2 F2RL3 JAM2 JAM3
Entrez ID		2151
HPRD ID		03561
Ensembl ID		ENSG00000164220
Uniprot IDs		O00254
PDB IDs
Enriched GO Terms of Interacting Partners?		Maintenance Of Blood-brain Barrier Bicellular Tight Junction Cell-cell Junction Anchoring Junction Tight Junction Cell-cell Adhesion Anatomical Structure Homeostasis Tissue Homeostasis Regulation Of Platelet Activation Hematopoietic Stem Cell Migration To Bone Marrow Protein Complex Involved In Cell Adhesion Positive Regulation Of Establishment Of Endothelial Barrier Protein Localization To Bicellular Tight Junction Leukocyte Migration Platelet Activation Hematopoietic Stem Cell Migration Protein Localization To Cell Junction Neutrophil-mediated Killing Of Bacterium Thrombin-activated Receptor Signaling Pathway Positive Regulation Of Platelet Aggregation Cell-cell Junction Assembly Cell Adhesion Regulation Of Establishment Of Endothelial Barrier Cellular Extravasation Protein Localization To Cell-cell Junction Cell Migration Positive Regulation Of Homotypic Cell-cell Adhesion Integrin Binding Neutrophil Mediated Immunity Multicellular Organismal-level Homeostasis Cell-cell Contact Zone Cell-cell Junction Organization Cell Motility Regulation Of Cytoskeleton Organization Regulation Of Platelet Aggregation Killing By Host Of Symbiont Cells Cell-cell Adhesion Mediator Activity Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Biological Process Involved In Interaction With Symbiont Regulation Of Endothelial Cell Differentiation Homeostatic Process Bicellular Tight Junction Assembly Cell Junction Assembly Tight Junction Assembly Adherens Junction Organization Tight Junction Organization Leukocyte Cell-cell Adhesion Positive Regulation Of Calcium Ion Transmembrane Transport Biofilm Matrix Disassembly Regulation Of Cytokinesis, Actomyosin Contractile Ring Assembly
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