CENPV

Description		centromere protein V
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Nucleus Nucleoplasm Chromosome Cytoplasm Spindle Cytosol Cytoskeleton Microtubule Cytoskeleton Midbody Nuclear Membrane Spindle Midzone
	Molecular Function	Protein Binding Carbon-sulfur Lyase Activity Metal Ion Binding
	Biological Process	Ameboidal-type Cell Migration Pericentric Heterochromatin Formation Positive Regulation Of Cytokinesis Regulation Of Chromosome Organization Centromere Complex Assembly Cell Division
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Amyotrophic lateral sclerosis ( 22959728 24931836) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) General risk tolerance (MTAG) ( 30643258)
Novel Interacting Genes		1 novel interacting genes: CYLD
Interacting Genes		1 interacting genes: CYLD
Entrez ID		201161
HPRD ID		12173
Ensembl ID		ENSG00000166582
Uniprot IDs		Q7Z7K6
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Interleukin-18-mediated Signaling Pathway Met1-linked Polyubiquitin Deubiquitinase Activity Ripoptosome Assembly Ripoptosome Assembly Involved In Necroptotic Process Protein Linear Deubiquitination Negative Regulation Of P38MAPK Cascade Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Proline-rich Region Binding K63-linked Deubiquitinase Activity Necroptotic Process K48-linked Deubiquitinase Activity Positive Regulation Of T Cell Receptor Signaling Pathway Programmed Necrotic Cell Death CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Protein K63-linked Deubiquitination Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Negative Regulation Of JNK Cascade Organelle Regulation Of Necroptotic Process T Cell Lineage Commitment Regulation Of B Cell Differentiation Regulation Of Programmed Necrotic Cell Death Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of P38MAPK Cascade Ciliary Tip Negative Regulation Of Type I Interferon Production Regulation Of T Cell Receptor Signaling Pathway Cytoplasmic Microtubule Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Canonical NF-kappaB Signal Transduction Negative Regulation Of DNA-binding Transcription Factor Activity Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Cilium Assembly Negative Regulation Of Canonical NF-kappaB Signal Transduction Cysteine-type Deubiquitinase Activity Regulation Of Non-canonical NF-kappaB Signal Transduction Protein Deubiquitination Negative Regulation Of Cytokine-mediated Signaling Pathway Cytoplasmic Pattern Recognition Receptor Signaling Pathway Negative Regulation Of Response To Cytokine Stimulus Cytoplasmic Side Of Plasma Membrane Protein Modification By Small Protein Removal Positive Regulation Of T Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Lymphocyte Differentiation Centriolar Satellite Regulation Of B Cell Activation Regulation Of Type I Interferon Production Cysteine-type Peptidase Activity
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