LDHD

Description		lactate dehydrogenase D
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane
	Molecular Function	Catalytic Activity Lactate Dehydrogenase Activity D-lactate Dehydrogenase (cytochrome) Activity Protein Binding D-lactate Dehydrogenase (NAD+) Activity Oxidoreductase Activity Flavin Adenine Dinucleotide Binding FAD Binding
	Biological Process	Lactate Catabolic Process
Pathways		Mitochondrial protein import Mitochondrial protein import Mitochondrial protein degradation
Drugs
Diseases
GWAS		Crohn's disease (time to surgery) ( 23665963) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Pancreatic cancer ( 25086665) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Novel Interacting Genes		2 novel interacting genes: CSRP3 IRAK1
Interacting Genes		2 interacting genes: CSRP3 IRAK1
Entrez ID		197257
HPRD ID		06318
Ensembl ID		ENSG00000166816
Uniprot IDs		Q86WU2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Actin Filament Severing Negative Regulation Of Actin Filament Severing Toll Signaling Pathway Toll-like Receptor 2 Signaling Pathway Detection Of Muscle Stretch Phospholipase C/protein Kinase C Signal Transduction T-tubule Organization Telethonin Binding Interleukin-33-mediated Signaling Pathway Toll-like Receptor 9 Signaling Pathway Interleukin-1-mediated Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Endolysosomal Toll-like Receptor Signaling Pathway Intracellular Signaling Cassette Muscle Cell Cellular Homeostasis Response To Muscle Stretch Regulation Of The Force Of Heart Contraction Cardiac Muscle Hypertrophy Muscle Hypertrophy Cardiac Myofibril Assembly Negative Regulation Of Myoblast Differentiation Actinin Binding Myofibril Assembly Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Cell Surface Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Lipopolysaccharide-mediated Signaling Pathway Structural Constituent Of Muscle Cardiac Muscle Contraction Detection Of Mechanical Stimulus Positive Regulation Of Myoblast Differentiation Sarcomere Organization Type I Interferon-mediated Signaling Pathway Toll-like Receptor Signaling Pathway Defense Response Cellular Response To Heat Cell Surface Pattern Recognition Receptor Signaling Pathway Sarcomere JNK Cascade Canonical NF-kappaB Signal Transduction Heat Shock Protein Binding Cardiac Muscle Tissue Development
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