AHSG

Description		alpha 2-HS glycoprotein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Extracellular Matrix Platelet Alpha Granule Lumen Secretory Granule Lumen Extracellular Exosome Blood Microparticle
	Molecular Function	Endopeptidase Inhibitor Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Kinase Inhibitor Activity
	Biological Process	Skeletal System Development Ossification Pinocytosis Acute-phase Response Regulation Of Bone Mineralization Negative Regulation Of Bone Mineralization Negative Regulation Of Insulin Receptor Signaling Pathway Regulation Of Inflammatory Response Positive Regulation Of Phagocytosis
Pathways		Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation
Drugs		Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Blood protein levels ( 30072576)
Novel Interacting Genes		9 novel interacting genes: CDC42 DCN FBXO2 FBXW7 GRB2 HSP90AA1 INSR RRAS2 VKORC1
Interacting Genes		9 interacting genes: CDC42 DCN FBXO2 FBXW7 GRB2 HSP90AA1 INSR RRAS2 VKORC1
Entrez ID		197
HPRD ID		00727
Ensembl ID		ENSG00000145192
Uniprot IDs		C9JV77 P02765
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Organelle Organization GTP Binding Insulin Receptor Substrate Binding Positive Regulation Of Lamellipodium Organization Positive Regulation Of Cellular Component Organization Positive Regulation Of Lamellipodium Assembly Neuron Projection Organization Regulation Of Lamellipodium Assembly Dendritic Spine Organization Postsynapse Organization Regulation Of MAPK Cascade Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Organelle Organization Positive Regulation Of Catabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Post-translational Protein Modification Small GTPase-mediated Signal Transduction Regulation Of Lamellipodium Organization Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Guanyl-nucleotide Exchange Factor Adaptor Activity CTP Binding DATP Binding Regulation Of Nitric Oxide Metabolic Process Regulation Of Nitric Oxide Biosynthetic Process SCF Ubiquitin Ligase Complex SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Receptor Internalization Regulation Of Cell Migration Neuronal Cell Body GBD Domain Binding Storage Vacuole Identical Protein Binding Lysosomal Lumen Positive Regulation Of Protein Polymerization Protein Phosphatase Binding Insulin Receptor Signaling Pathway Grb2-EGFR Complex Ras Protein Signal Transduction Regulation Of Protein Catabolic Process Neurofibrillary Tangle Assembly UTP Binding Sulfonylurea Receptor Binding Amyloid-beta Binding Denatured Protein Binding Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity
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