ABAT

Description		4-aminobutyrate aminotransferase
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix 4-aminobutyrate Transaminase Complex
	Molecular Function	Transaminase Activity Transferase Activity Pyridoxal Phosphate Binding Succinate-semialdehyde Dehydrogenase Binding 4-aminobutyrate:2-oxoglutarate Transaminase Activity Identical Protein Binding Metal Ion Binding (S)-3-amino-2-methylpropionate Transaminase Activity Iron-sulfur Cluster Binding
	Biological Process	Response To Hypoxia Copulation Locomotory Behavior Response To Xenobiotic Stimulus Gamma-aminobutyric Acid Metabolic Process Gamma-aminobutyric Acid Biosynthetic Process Gamma-aminobutyric Acid Catabolic Process Response To Iron Ion Negative Regulation Of Gamma-aminobutyric Acid Secretion Cerebellum Development Positive Regulation Of Heat Generation Positive Regulation Of Insulin Secretion Negative Regulation Of Dopamine Secretion Response To Nicotine Exploration Behavior Response To Cocaine Response To Ethanol Negative Regulation Of Blood Pressure Positive Regulation Of Dopamine Metabolic Process Nervous System Process Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Inhibitory Postsynaptic Potential Positive Regulation Of Prolactin Secretion Positive Regulation Of Aspartate Secretion
Pathways		Degradation of GABA
Drugs		Pyridoxal phosphate Pyruvic acid Glutamic acid Alanine Phenelzine Vigabatrin (4e)-4-Aminohex-4-Enoic Acid 4-Amino Hexanoic Acid
Diseases
GWAS		Anger ( 24489884) Bronchopulmonary dysplasia in preterm infants ( 30113228) Menopause (age at onset) ( 26414677) Response to opioid analgesics in cancer (pain decrease) ( 30277654)
Novel Interacting Genes		1 novel interacting genes: ALDH5A1
Interacting Genes		1 interacting genes: ALDH5A1
Entrez ID		18
HPRD ID		00661
Ensembl ID		ENSG00000183044
Uniprot IDs		H3BNQ7 P80404 X5D8S1
PDB IDs
Enriched GO Terms of Interacting Partners?		Succinate-semialdehyde Dehydrogenase [NAD(P)+] Activity Succinate-semialdehyde Dehydrogenase (NAD+) Activity Gamma-aminobutyric Acid Catabolic Process Gamma-aminobutyric Acid Metabolic Process Succinate Metabolic Process Oxidoreductase Activity, Acting On The Aldehyde Or Oxo Group Of Donors, NAD Or NADP As Acceptor Glutamate Metabolic Process Synaptic Transmission, GABAergic Glutamine Family Amino Acid Metabolic Process Post-embryonic Development Dicarboxylic Acid Metabolic Process Amino Acid Catabolic Process Central Nervous System Development L-amino Acid Metabolic Process Alpha-amino Acid Metabolic Process Carboxylic Acid Catabolic Process Amino Acid Metabolic Process Trans-synaptic Signaling Synaptic Signaling Chemical Synaptic Transmission Mitochondrial Matrix Monocarboxylic Acid Metabolic Process
Tagcloud ?