DYNC1LI2

Description		dynein cytoplasmic 1 light intermediate chain 2
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GO Annotations	Cellular Component	Kinetochore Cytoplasm Late Endosome Centrosome Cytosol Cytoskeleton Cytoplasmic Dynein Complex Microtubule Membrane Dynein Complex
	Molecular Function	Nucleotide Binding ATP Binding Identical Protein Binding Dynein Heavy Chain Binding
	Biological Process	Microtubule Cytoskeleton Organization Microtubule-based Movement Positive Regulation Of Intracellular Transport Centrosome Localization Cellular Response To Nerve Growth Factor Stimulus
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Lipid traits ( 30576415)
Novel Interacting Genes		10 novel interacting genes: APP BRCA2 CTRL DMTN FCSK GAA HPR LINC00632 OGT ZFHX3
Interacting Genes		10 interacting genes: APP BRCA2 CTRL DMTN FCSK GAA HPR LINC00632 OGT ZFHX3
Entrez ID		1783
HPRD ID		09923
Ensembl ID		ENSG00000135720
Uniprot IDs		O43237
PDB IDs		6F1T 6F1Y 6F38 6F3A 7Z8F 7Z8I 7Z8J 7Z8K 7Z8L 8PR0 8PR1 8PR2 8PR3 8PTK
Enriched GO Terms of Interacting Partners?		Hemopoiesis Acetylcholine Receptor Activator Activity Amyloid-beta Complex Regulation Of Cell Junction Assembly Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Myeloid Cell Development Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Amylin Binding Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Toll Signaling Pathway Cellular Homeostasis Cellular Response To CAMP Cell Development Lipoprotein Particle Positive Regulation Of Protein Import Response To CAMP Circadian Regulation Of Gene Expression Regulation Of Locomotor Rhythm Mitotic Recombination-dependent Replication Fork Processing BRCA2-MAGE-D1 Complex Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Autolysosome Lumen Sucrose Metabolic Process Vacuolar Sequestering Maltose Metabolic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Fucokinase Activity GDP-L-fucose Salvage PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Diaphragm Contraction Alpha-1,4-glucosidase Activity Protein O-acetylglucosaminyltransferase Activity Regulation Of Spontaneous Synaptic Transmission Response To Purine-containing Compound Positive Regulation Of Mitotic Cell Cycle Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle
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