DLX3

Description		distal-less homeobox 3
Image
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Blood Vessel Development Placenta Development Hair Follicle Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Gene Expression Wnt Signaling Pathway BMP Signaling Pathway Epithelial Cell Differentiation Hair Follicle Morphogenesis Hair Cell Differentiation Odontogenesis Of Dentin-containing Tooth Hair Cycle Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Development Hair Follicle Cell Proliferation Odontoblast Differentiation
Pathways
Drugs
Diseases		Trichodentoosseous dysplasia Amelogenesis imperfecta hypoplastic-hypomaturation with taurodontism (AIHHT)
GWAS		Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701)
Novel Interacting Genes		5 novel interacting genes: BANP POU4F2 PRKCA TBL1X TDP2
Interacting Genes		5 interacting genes: BANP POU4F2 PRKCA TBL1X TDP2
Entrez ID		1747
HPRD ID		02752
Ensembl ID		ENSG00000064195
Uniprot IDs		O60479
PDB IDs		4XRS
Enriched GO Terms of Interacting Partners?		Response To Estradiol Nucleoplasm Regulation Of Myeloid Leukocyte Differentiation Negative Regulation Of Amacrine Cell Differentiation Axonogenesis Sensory Perception Of Mechanical Stimulus Positive Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Myeloid Cell Differentiation Sensory Perception Of Sound Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Angiotensin-activated Signaling Pathway Histone H3T6 Kinase Activity Alphav-beta3 Integrin-PKCalpha Complex 5'-tyrosyl-DNA Phosphodiesterase Activity Tyrosyl-RNA Phosphodiesterase Activity Tyrosyl-DNA Phosphodiesterase Activity Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Retinal Ganglion Cell Axon Guidance Positive Regulation Of Leukocyte Differentiation Negative Regulation Of Biosynthetic Process Nervous System Process Dorsal Root Ganglion Development Regulation Of Angiotensin-activated Signaling Pathway Protein Kinase C Signaling Transcription Corepressor Activity Regulation Of Myeloid Cell Differentiation Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Desmosome Assembly Positive Regulation Of Nervous System Development Negative Regulation Of Adipose Tissue Development Neuron Projection Morphogenesis Negative Regulation Of Macromolecule Metabolic Process Cell Projection Morphogenesis Negative Regulation Of Metabolic Process Positive Regulation Of Transcription Regulatory Region DNA Binding Response To Peptide Hormone Apoptotic Signaling Pathway Regulation Of Axon Guidance Mitotic Nuclear Membrane Disassembly Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Response To Phorbol 13-acetate 12-myristate Negative Regulation Of Glial Cell Apoptotic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Bone Resorption Diacylglycerol Binding Ganglion Development Desmosome Organization Positive Regulation Of Macrophage Differentiation
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