DLX1

Description		distal-less homeobox 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Proximal/distal Pattern Formation Neuroblast Differentiation Subpallium Development Hippocampus Development Forebrain Neuron Differentiation Cerebral Cortex GABAergic Interneuron Differentiation Cerebral Cortex GABAergic Interneuron Fate Commitment Cell Differentiation Negative Regulation Of BMP Signaling Pathway Odontogenesis Of Dentin-containing Tooth Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Cell Differentiation Negative Regulation Of Notch Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Photoreceptor Cell Differentiation Embryonic Skeletal System Development Oligodendrocyte Differentiation Negative Regulation Of Oligodendrocyte Differentiation Neuron Apoptotic Process Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Response To BMP Stimulus GABAergic Neuron Differentiation Positive Regulation Of Amacrine Cell Differentiation Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23535729)
Novel Interacting Genes		1 novel interacting genes: SMAD4
Interacting Genes		1 interacting genes: SMAD4
Entrez ID		1745
HPRD ID		08961
Ensembl ID		ENSG00000144355
Uniprot IDs		P56177 X5D2F9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis Activin Responsive Factor Complex Left Ventricular Cardiac Muscle Tissue Morphogenesis Gonad Morphogenesis Nephrogenic Mesenchyme Morphogenesis Metanephric Mesenchyme Morphogenesis SMAD Protein Complex Positive Regulation Of Luteinizing Hormone Secretion Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Atrioventricular Valve Formation Sebaceous Gland Development Heteromeric SMAD Protein Complex Formation Of Anatomical Boundary Brainstem Development Mesendoderm Development Sulfate Binding Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of Transforming Growth Factor Beta2 Production Endocardial Cell Differentiation Atrioventricular Canal Development Somite Rostral/caudal Axis Specification Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Cardiac Muscle Cell Differentiation Endothelial Cell Activation Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Negative Regulation Of Cardiocyte Differentiation Secondary Palate Development Filamin Binding Neural Crest Cell Differentiation Heart Valve Formation Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Cardiac Muscle Cell Apoptotic Process I-SMAD Binding Cardiac Conduction System Development Interleukin-6-mediated Signaling Pathway Gastrulation With Mouth Forming Second Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of Cardiac Muscle Cell Differentiation Seminiferous Tubule Development Regulation Of Hair Follicle Development Regulation Of Extracellular Matrix Assembly Uterus Development Female Gonad Development Positive Regulation Of Extracellular Matrix Organization Outflow Tract Septum Morphogenesis SMAD Protein Signal Transduction Regulation Of Hair Cycle
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