Wiki-MPM

  • About
  • Search
  • Browse
  • People
  • Funding
  • Updates

DHCR24

Description 24-dehydrocholesterol reductase
Image No pdb structure
GO Annotations Cellular Component
  • Golgi Membrane
  • Nucleus
  • Cytoplasm
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Membrane
  • Integral Component Of Membrane
Molecular Function
  • Delta24(24-1) Sterol Reductase Activity
  • Protein Binding
  • Oxidoreductase Activity, Acting On The CH-CH Group Of Donors, NAD Or NADP As Acceptor
  • Enzyme Binding
  • Peptide Antigen Binding
  • Delta24-sterol Reductase Activity
  • FAD Binding
Biological Process
  • Cholesterol Biosynthetic Process
  • Apoptotic Process
  • Response To Oxidative Stress
  • Cell Cycle Arrest
  • Steroid Metabolic Process
  • Tissue Development
  • Cholesterol Biosynthetic Process Via Desmosterol
  • Cholesterol Biosynthetic Process Via Lathosterol
  • Negative Regulation Of Apoptotic Process
  • Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
  • Skin Development
  • Regulation Of Neuron Death
Pathways
  • Cholesterol biosynthesis via desmosterol
  • Cholesterol biosynthesis via lathosterol
Drugs
Diseases
  • Desmosterolosis
GWAS
  • Visceral fat, circulating phospholipid PC(16:0/2:0) and white matter microstructure (shared variance) ( 31900429)
Interacting Genes 2 interacting genes: CCR4 TP53
Entrez ID 1718
HPRD ID 05916
Ensembl ID ENSG00000116133
Uniprot IDs Q15392
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025