BMPER

Description		BMP binding endothelial regulator
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix
	Molecular Function	Extracellular Matrix Structural Constituent
	Biological Process	Blood Vessel Development Ureteric Bud Development Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Endothelial Cell Migration BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Regulation Of Protein Localization Tube Development Endothelial Cell Activation Regulation Of Angiogenesis System Development Inner Ear Development Positive Regulation Of SMAD Protein Signal Transduction SMAD Protein Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Sprouting Angiogenesis
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease ( 24770881) Asthma ( 29273806) Corneal astigmatism ( 29422769) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243) Longevity ( 33657282) Post bronchodilator FEV1 ( 26634245) Uterine fibroid number (single vs multiple) ( 30196971)
Novel Interacting Genes		3 novel interacting genes: BMP2 BMP4 BMP6
Interacting Genes		3 interacting genes: BMP2 BMP4 BMP6
Entrez ID		168667
HPRD ID		16368
Ensembl ID		ENSG00000164619
Uniprot IDs		A0A090N7U6 A0A3B3ITW7 Q8N8U9
PDB IDs
Enriched GO Terms of Interacting Partners?		BMP Receptor Binding Positive Regulation Of Cartilage Development Cellular Response To BMP Stimulus Positive Regulation Of Bone Mineralization Positive Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Ossification Regulation Of SMAD Protein Signal Transduction Regulation Of Cartilage Development Positive Regulation Of Osteoblast Differentiation Bone Development Positive Regulation Of Epithelial Cell Differentiation Enzyme Activator Complex Regulation Of Bone Mineralization BMP Signaling Pathway Cardiac Jelly Development Positive Regulation Of Neuron Differentiation Cartilage Development Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Telencephalon Regionalization Regulation Of Ossification Osteoblast Differentiation Ossification Ameloblast Differentiation Positive Regulation Of Odontoblast Differentiation Regulation Of Aldosterone Biosynthetic Process Heart Induction Positive Regulation Of Neuroepithelial Cell Differentiation Regulation Of Osteoblast Differentiation Growth Factor Activity Regulation Of Odontogenesis Of Dentin-containing Tooth Regulation Of Heart Morphogenesis Regulation Of Epithelial Cell Differentiation Regulation Of Odontoblast Differentiation Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Lung Vasculature Development Skeletal System Development Co-receptor Binding Regulation Of Neuron Differentiation Type B Pancreatic Cell Development Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cell-cell Adhesion Positive Regulation Of Endothelial Cell Differentiation Cytokine Activity Regulation Of Odontogenesis Regulation Of Steroid Hormone Biosynthetic Process Regulation Of Cardiac Muscle Cell Differentiation Heart Development Cellular Response To Growth Factor Stimulus Regulation Of Ketone Biosynthetic Process
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