AEBP1

Description		AE binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Extracellular Matrix Extracellular Exosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Carboxypeptidase Activity Metallocarboxypeptidase Activity Extracellular Matrix Structural Constituent Calmodulin Binding Collagen Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Proteolysis Peptide Metabolic Process Protein Processing Regulation Of Collagen Fibril Organization
Pathways
Drugs
Diseases
GWAS		Carpal tunnel syndrome ( 30833571)
Novel Interacting Genes		3 novel interacting genes: GRB2 TCF3 VASP
Interacting Genes		3 interacting genes: GRB2 TCF3 VASP
Entrez ID		165
HPRD ID		04281
Ensembl ID		ENSG00000106624
Uniprot IDs		Q8IUX7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Actin Filament Polymerization Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Regulation Of Actin Polymerization Or Depolymerization SH3 Domain Binding Guanyl-nucleotide Exchange Factor Adaptor Activity Regulation Of Actin Filament Length Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cytoskeleton Organization Grb2-EGFR Complex Vitamin D Response Element Binding Regulation Of Cellular Component Size Regulation Of Actin Filament Organization Positive Regulation Of Lymphocyte Activation Actin Filament-based Process Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Filament-based Process Branching Involved In Labyrinthine Layer Morphogenesis Actin Cytoskeleton Organization Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cell Activation Regulation Of Supramolecular Fiber Organization Neurotrophin TRKA Receptor Binding B Cell Lineage Commitment Immunoglobulin V(D)J Recombination Profilin Binding Lymphocyte Activation Insulin Receptor Substrate Binding Positive Regulation Of Cellular Component Biogenesis Regulation Of Cytoskeleton Organization Regulation Of Lymphocyte Activation Positive Regulation Of Organelle Organization Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Mitogen-activated Protein Kinase Kinase Kinase Binding Leukocyte Activation Filopodium Membrane Schwann Cell Development V(D)J Recombination Cell Activation Regulation Of Cell Activation Lamellipodium Membrane Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Ephrin Receptor Binding BHLH Transcription Factor Binding Epidermal Growth Factor Receptor Binding COP9 Signalosome Insulin-like Growth Factor Receptor Signaling Pathway Somatic Recombination Of Immunoglobulin Gene Segments Endodermal Cell Differentiation
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