WBP2NL

Description		WBP2 N-terminal like
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Perinuclear Theca Sperm Flagellum Sperm Head
	Molecular Function	Transcription Coactivator Activity Protein Binding Chromatin DNA Binding WW Domain Binding
	Biological Process	Egg Activation Male Pronucleus Assembly Positive Regulation Of DNA-templated Transcription Meiotic Cell Cycle Regulation Of Cytosolic Calcium Ion Concentration
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Breast size ( 22747683) Estimated glomerular filtration rate ( 31217584) Feeling tense ( 29500382) Intelligence ( 28530673) Isthmus-cingulate cortex volume ( 31530798) Platelet distribution width ( 27863252) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Novel Interacting Genes		2 novel interacting genes: CD28 CHADL
Interacting Genes		2 interacting genes: CD28 CHADL
Entrez ID		164684
HPRD ID		14512
Ensembl ID		ENSG00000183066
Uniprot IDs		Q6ICG8
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Complex Involved In Cell Adhesion Alpha-beta T Cell Proliferation Regulatory T Cell Differentiation Negative Thymic T Cell Selection Positive Regulation Of Inflammatory Response To Antigenic Stimulus Negative T Cell Selection Regulation Of Isotype Switching To IgG Isotypes Positive Regulation Of Isotype Switching To IgG Isotypes CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Collagen Fibril Binding Extracellular Matrix Structural Constituent Conferring Compression Resistance Regulation Of Collagen Fibril Organization Negative Regulation Of Collagen Fibril Organization Positive Regulation Of Interleukin-10 Production Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation Regulation Of Isotype Switching Positive Regulation Of Immunoglobulin Mediated Immune Response Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of Interleukin-4 Production T Cell Costimulation Regulation Of Interleukin-4 Production Thymic T Cell Selection Positive Regulation Of Isotype Switching Immunological Synapse Regulation Of Regulatory T Cell Differentiation T Cell Selection Positive Regulation Of Viral Genome Replication Positive Regulation Of Interleukin-2 Production Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Alpha-beta T Cell Proliferation Negative Regulation Of Extracellular Matrix Organization Negative Regulation Of Chondrocyte Differentiation Negative Regulation Of Cartilage Development Positive Regulation Of Immunoglobulin Production Regulation Of Interleukin-2 Production Coreceptor Activity Regulation Of Interleukin-10 Production Regulation Of Multicellular Organismal Development CD4-positive, Alpha-beta T Cell Activation Positive Regulation Of Viral Process Regulation Of Chondrocyte Differentiation Collagen Binding Regulation Of Extracellular Matrix Organization Regulation Of Cell Differentiation Positive Regulation Of DNA Recombination Regulation Of Viral Genome Replication T Cell Proliferation Positive Regulation Of Alpha-beta T Cell Activation Regulation Of Cartilage Development
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