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DCX
Description
doublecortin
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Cytoskeleton
Microtubule
Microtubule Associated Complex
Cell Projection
Neuron Projection
Molecular Function
Protein Binding
Microtubule Binding
Protein Kinase Binding
Biological Process
Neuron Migration
Nervous System Development
Central Nervous System Development
Cell Differentiation
Axoneme Assembly
Intracellular Signal Transduction
Retina Development In Camera-type Eye
Pathways
Neurofascin interactions
Drugs
Diseases
Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS
Novel Interacting Genes
39 novel interacting genes:
ACD
AP1M1
AP2M1
APP
BICD2
CALCOCO2
CDK5
FBXO25
FSD2
GOLGA2
HOOK2
IKZF1
KIFC3
KRT40
KRTAP10-8
MAPK9
MEOX1
MEOX2
MID2
MTUS2
NFASC
PAFAH1B1
POT1
PPP1CA
PPP1R9B
RBM5
RINT1
SPAG5
SPP1
TERF1
TINF2
TRIM23
TRIM27
TRIM39
USP9X
VPS52
ZBTB10
ZBTB5
ZRANB1
Interacting Genes
39 interacting genes:
ACD
AP1M1
AP2M1
APP
BICD2
CALCOCO2
CDK5
FBXO25
FSD2
GOLGA2
HOOK2
IKZF1
KIFC3
KRT40
KRTAP10-8
MAPK9
MEOX1
MEOX2
MID2
MTUS2
NFASC
PAFAH1B1
POT1
PPP1CA
PPP1R9B
RBM5
RINT1
SPAG5
SPP1
TERF1
TINF2
TRIM23
TRIM27
TRIM39
USP9X
VPS52
ZBTB10
ZBTB5
ZRANB1
Entrez ID
1641
HPRD ID
02127
Ensembl ID
ENSG00000077279
Uniprot IDs
A0A1B0GWD1
A0A7P0T9C5
A0A804CF28
A8K340
O43602
PDB IDs
1MJD
2BQQ
2XRP
4ATU
5IKC
5IN7
5IO9
5IOI
5IP4
6FNZ
6REV
6RF2
6RF8
6RFD
Enriched GO Terms of Interacting Partners
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Shelterin Complex
Microtubule Binding
Telomeric DNA Binding
Nuclear Telomere Cap Complex
Telomere Capping
Telomere Assembly
Intracellular Protein Localization
Negative Regulation Of Telomere Maintenance Via Telomerase
Intracellular Transport
Establishment Of Localization In Cell
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Microtubule
Negative Regulation Of Telomere Maintenance
Cellular Localization
Protein Transport
Establishment Of Protein Localization
Telomere Maintenance
Chromosome, Telomeric Region
Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Cellular Component Organization
Acetylcholine Receptor Activator Activity
Regulation Of Telomere Maintenance Via Telomere Lengthening
Regulation Of Cellular Component Organization
Telomere Organization
Cytoskeleton
Growth Cone
Organelle Organization
Positive Regulation Of Organelle Organization
Telomere Maintenance Via Telomerase
Positive Regulation Of Telomere Maintenance
RNA-templated DNA Biosynthetic Process
Negative Regulation Of Chromosome Organization
Vesicle-mediated Transport
Telomere Maintenance Via Telomere Lengthening
Regulation Of DNA Biosynthetic Process
Regulation Of Organelle Organization
Somite Specification
Cell Division
Regulation Of Establishment Of Protein Localization To Telomere
Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein Binding
Positive Regulation Of Chromosome Organization
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Establishment Of Protein Localization To Chromosome
Telomerase Inhibitor Activity
Establishment Of Protein Localization To Telomere
Supramolecular Fiber Organization
Regulation Of Telomere Maintenance
Chromosome Organization
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