KANK4

Description		KN motif and ankyrin repeat domains 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Microtubule Cytoskeleton
	Molecular Function	Protein Binding
	Biological Process	Negative Regulation Of Actin Filament Polymerization
Pathways
Drugs
Diseases
GWAS		Fuchs's corneal dystrophy ( 28358029) Regular attendance at a gym or sports club ( 29970889)
Novel Interacting Genes		6 novel interacting genes: CSK CUL5 HAT1 HOMER3 MYLIP TRAPPC6A
Interacting Genes		6 interacting genes: CSK CUL5 HAT1 HOMER3 MYLIP TRAPPC6A
Entrez ID		163782
HPRD ID		14109
Ensembl ID		ENSG00000132854
Uniprot IDs		B1ALP6 B3KXJ6 Q5T7N3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Low-density Lipoprotein Particle Clearance Negative Regulation Of Low-density Lipoprotein Particle Clearance Negative Regulation Of Lipoprotein Particle Clearance Negative Regulation Of Multicellular Organismal Process Symbiont-mediated Suppression Of Host Innate Immune Response Protein Modification Process Negative Regulation Of Focal Adhesion Disassembly G Protein-coupled Glutamate Receptor Binding Negative Regulation Of Cellular Component Organization Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Golgi To Plasma Membrane Protein Transport Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Cytoplasm Negative Regulation Of Cytokine Production Negative Regulation Of Bone Resorption Protein Kinase A Catalytic Subunit Binding Regulation Of Golgi To Plasma Membrane Protein Transport Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Negative Regulation Of Cell Adhesion Negative Regulation Of Gene Expression Regulation Of Growth Hormone Receptor Signaling Pathway Growth Hormone Receptor Signaling Pathway Via JAK-STAT Cul5-RING Ubiquitin Ligase Complex Ubiquitin Ligase Complex Scaffold Activity Negative Regulation Of CGAS/STING Signaling Pathway Erythropoietin-mediated Signaling Pathway Cullin-RING Ubiquitin Ligase Complex Negative Regulation Of Growth Hormone Receptor Signaling Pathway Reelin-mediated Signaling Pathway Ubiquitin-protein Transferase Activity Internal Protein Amino Acid Acetylation Subtelomeric Heterochromatin Formation Histone H4 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Negative Regulation Of Calcineurin-NFAT Signaling Cascade G Protein-coupled Glutamate Receptor Signaling Pathway Regulation Of Store-operated Calcium Entry Basal Part Of Cell TRAPP Complex TRAPPIII Protein Complex
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