ECI1

Description		enoyl-CoA delta isomerase 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix
	Molecular Function	Catalytic Activity Delta(3)-delta(2)-enoyl-CoA Isomerase Activity Isomerase Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation
Pathways		mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Mitochondrial protein degradation
Drugs		Octanoyl-Coenzyme A Benzamidine
Diseases
GWAS		Anthropometric traits (multi-trait analysis) ( 30166351) Serum alkaline phosphatase levels ( 33547301)
Novel Interacting Genes		3 novel interacting genes: APP MAPKAP1 POT1
Interacting Genes		3 interacting genes: APP MAPKAP1 POT1
Entrez ID		1632
HPRD ID		02628
Ensembl ID		ENSG00000167969
Uniprot IDs		A0A384NKJ3 P42126
PDB IDs		1SG4
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Early Endosome Membrane Amylin Binding Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Regulation Of Cellular Response To Stress Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Telomeric D-loop Binding Telomere Assembly Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Single-stranded Telomeric DNA Binding Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Early Endosome Regulation Of Toll Signaling Pathway Shelterin Complex Axon Choice Point Recognition Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Heparan Sulfate Binding
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