SLFN5

Description		schlafen family member 5
Image
GO Annotations	Cellular Component	Nucleus
	Molecular Function	Nucleotide Binding RNA Nuclease Activity ATP Binding Ribosome Binding
	Biological Process	RRNA Catabolic Process Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes		4 novel interacting genes: AKT1 CLK1 SRPK2 UBC
Interacting Genes		4 interacting genes: AKT1 CLK1 SRPK2 UBC
Entrez ID		162394
HPRD ID		17519
Ensembl ID		ENSG00000166750
Uniprot IDs		B4E128 Q08AF3
PDB IDs		6RR9 7CUX 7PPJ 7Q3Z
Enriched GO Terms of Interacting Partners?		Protein Serine/threonine/tyrosine Kinase Activity Peptidyl-serine Phosphorylation Protein Serine Kinase Activity 14-3-3 Protein Binding Protein Serine/threonine Kinase Activity Protein Kinase Activity Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Kinase Activity Regulation Of TRNA Methylation Response To Rapamycin Positive Regulation Of Protein Localization To Endoplasmic Reticulum Nitric-oxide Synthase Regulator Activity Regulation Of Neuron Apoptotic Process Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Negative Regulation Of SREBP Signaling Pathway Response To Insulin-like Growth Factor Stimulus Negative Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of TORC2 Signaling TRNA Stabilization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Potassium Channel Activator Activity Vesicle Mammalian Oogenesis Stage RNA (guanine-N7)-methylation Negative Regulation Of Fatty Acid Transport Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Cellular Response To Peptide Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Maintenance Of Protein Location In Mitochondrion TRNA (guanine-N7)-methylation Activation-induced Cell Death Of T Cells Regulation Of Long-chain Fatty Acid Import Into Cell TORC2 Complex Binding Cellular Response To Rapamycin Peripheral Nervous System Myelin Maintenance Regulation Of Endodeoxyribonuclease Activity Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Deoxyribonuclease Activity Negative Regulation Of Protein Localization To Lysosome Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Endodeoxyribonuclease Activity SREBP-SCAP Complex Retention In Endoplasmic Reticulum Regulation Of RNA Splicing Nuclear Speck Organization ATP Binding Regulation Of MRNA Metabolic Process Positive Regulation Of Cell Cycle Vascular Endothelial Cell Response To Laminar Fluid Shear Stress
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