CEP120

Description		centrosomal protein 120
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GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytoskeleton
	Molecular Function	Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Centrosome Cycle Cell Population Proliferation Regulation Of Centrosome Duplication Positive Regulation Of Centrosome Duplication Cerebral Cortex Development Neurogenesis Interkinetic Nuclear Migration Astral Microtubule Organization Regulation Of Protein Localization Regulation Of Microtubule-based Process Positive Regulation Of Cilium Assembly Positive Regulation Of Cell Cycle Process Positive Regulation Of Organelle Assembly Positive Regulation Of Centriole Elongation Positive Regulation Of Establishment Of Protein Localization
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Appendicular lean mass ( 33097823) Body mass index ( 28892062) Coronary artery disease ( 29212778) Height ( 20881960 25429064 31562340) Multisite chronic pain ( 31194737) Obesity (extreme) ( 30677029) Pulse pressure ( 30578418) Virologic severity in Herpes simplex virus type 2 infection ( 29535370) Waist circumference ( 26785701)
Novel Interacting Genes		2 novel interacting genes: PEA15 STAT3
Interacting Genes		2 interacting genes: PEA15 STAT3
Entrez ID		153241
HPRD ID		08769
Ensembl ID		ENSG00000168944
Uniprot IDs		A0A6Q8PF83 A0A6Q8PH95 B4DLH5 Q8N960
PDB IDs		4ICW 4ICX 6FLJ 6FLK
Enriched GO Terms of Interacting Partners?		Regulation Of Hydrogen Peroxide Metabolic Process Interleukin-10-mediated Signaling Pathway RNA Sequestering Activity Negative Regulation Of MiRNA-mediated Gene Silencing Regulation Of MiRNA Processing Negative Regulation Of Primary MiRNA Processing Cellular Response To Leptin Stimulus Growth Hormone Receptor Signaling Pathway Via JAK-STAT Regulation Of Inflammatory Response To Wounding Inflammatory Response To Wounding Interleukin-2-mediated Signaling Pathway Negative Regulation Of Hydrogen Peroxide Metabolic Process Nuclear Glucocorticoid Receptor Binding Postsynapse To Nucleus Signaling Pathway Regulation Of Skeletal Muscle Satellite Cell Proliferation Interleukin-9-mediated Signaling Pathway Negative Regulation Of Neuron Migration Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA Interleukin-11-mediated Signaling Pathway Positive Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Skeletal Muscle Cell Proliferation Retinal Rod Cell Differentiation Negative Regulation Of 3'-UTR-mediated MRNA Stabilization Regulation Of Regulatory NcRNA Processing Sexual Reproduction Interleukin-23-mediated Signaling Pathway Cellular Response To Interleukin-17 Positive Regulation Of ATP Biosynthetic Process Regulation Of Skeletal Muscle Cell Proliferation Camera-type Eye Photoreceptor Cell Differentiation Interleukin-15-mediated Signaling Pathway Negative Regulation Of MiRNA Processing T-helper 17 Type Immune Response Negative Regulation Of Inflammatory Response To Wounding Primary MiRNA Binding Interleukin-6-mediated Signaling Pathway Leptin-mediated Signaling Pathway Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation T-helper 17 Cell Lineage Commitment Radial Glial Cell Differentiation CCR5 Chemokine Receptor Binding Negative Regulation Of D-glucose Import Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Negative Regulation Of Glycolytic Process Photoreceptor Cell Differentiation Eye Photoreceptor Cell Differentiation T-helper Cell Lineage Commitment Response To Leptin
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