NEK10

Description		NIMA related kinase 10
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Protein Kinase Complex
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of MAP Kinase Activity Regulation Of ERK1 And ERK2 Cascade Mucociliary Clearance Regulation Of Cell Cycle G2/M Phase Transition
Pathways
Drugs
Diseases
GWAS		Arterial stiffness (carotid-femoral pulse wave velocity) ( 32790701) Body size at age 10 ( 32376654) Breast cancer ( 19330027) Cancer (pleiotropy) ( 27197191) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Gut microbiota (functional units) ( 27694959) Late-onset Alzheimer's disease ( 27770636) Mean arterial pressure ( 27618448) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Triglycerides ( 26160806) Uterine fibroids ( 30194396)
Novel Interacting Genes		2 novel interacting genes: HSPB1 MAP3K1
Interacting Genes		2 interacting genes: HSPB1 MAP3K1
Entrez ID		152110
HPRD ID		08135
Ensembl ID		ENSG00000163491
Uniprot IDs		A0A650C2C8 A0A8I5KTB8 Q6ZWH5 Q8N774
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Kinase C Signaling Regulation Of Protein Kinase C Signaling Positive Regulation Of Endothelial Cell Chemotaxis Protein Kinase Binding Protein Transport Along Microtubule Anterograde Axonal Protein Transport Protein Kinase C Inhibitor Activity Contractile Muscle Fiber MAP Kinase Kinase Kinase Activity Fc-epsilon Receptor Signaling Pathway Protein Refolding Cellular Response To Vascular Endothelial Growth Factor Stimulus Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Tight Junction Protein Localization To Synapse Positive Regulation Of Blood Vessel Endothelial Cell Migration Protein Folding Chaperone Protein Kinase C Binding Platelet Aggregation Axon Cytoplasm Positive Regulation Of Interleukin-1 Beta Production Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Axonal Transport Anterograde Axonal Transport Cornified Envelope Proteasome Complex Homotypic Cell-cell Adhesion Fc Receptor Signaling Pathway Positive Regulation Of Interleukin-1 Production Cellular Response To Mechanical Stimulus
Tagcloud ?