AIFM3

Description		AIF family member 3
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Endoplasmic Reticulum Cytosol
	Molecular Function	Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H Metal Ion Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Apoptotic Process Execution Phase Of Apoptosis
Pathways
Drugs
Diseases
GWAS		Keratoconus ( 33649486) Neuritic plaque ( 25188341) Testicular germ cell tumor ( 28604728)
Novel Interacting Genes		2 novel interacting genes: APP PRNP
Interacting Genes		2 interacting genes: APP PRNP
Entrez ID		150209
HPRD ID		08085
Ensembl ID		ENSG00000183773
Uniprot IDs		B7Z376 Q96NN9
PDB IDs		5O9V 6QRM 6SJZ 6SK3 6SK8 6SKJ
Enriched GO Terms of Interacting Partners?		Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Negative Regulation Of Long-term Synaptic Potentiation Intracellular Copper Ion Homeostasis Copper Ion Homeostasis Cellular Response To Copper Ion Molecular Function Activator Activity Response To Copper Ion Neuron Projection Organization Regulation Of Long-term Synaptic Potentiation Regulation Of Amyloid Precursor Protein Catabolic Process Cellular Response To Amyloid-beta Positive Regulation Of Calcium-mediated Signaling Response To Amyloid-beta Positive Regulation Of Neuron Apoptotic Process Regulation Of Calcium-mediated Signaling Protein-folding Chaperone Binding Regulation Of Type II Interferon Production Memory Regulation Of Postsynapse Organization Regulation Of Calcium Ion Transmembrane Transport Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To Metal Ion Type 8 Metabotropic Glutamate Receptor Binding Protein Homooligomerization Regulation Of Synaptic Plasticity Membrane Raft Regulation Of Calcium Ion Transport Postsynapse Acetylcholine Receptor Activator Activity Regulation Of Neuron Apoptotic Process Protein Complex Oligomerization Lipoprotein Particle Positive Regulation Of Protein Import Regulation Of Monoatomic Cation Transmembrane Transport Learning Or Memory PTB Domain Binding Cognition Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Synapse Organization Positive Regulation Of Establishment Of Protein Localization Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Monoatomic Ion Transmembrane Transport
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