AANAT

Description		aralkylamine N-acetyltransferase
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GO Annotations	Cellular Component	Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Aralkylamine N-acetyltransferase Activity Arylamine N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups 14-3-3 Protein Binding
	Biological Process	N-terminal Protein Amino Acid Acetylation Circadian Rhythm Response To Light Stimulus Photoperiodism Response To Zinc Ion Melatonin Biosynthetic Process Response To Insulin Response To Cytokine Response To Prostaglandin E Indolalkylamine Biosynthetic Process Response To Copper Ion Rhythmic Process Response To Corticosterone Response To CAMP Response To Calcium Ion Cellular Response To CAMP Response To Peptide
Pathways		Serotonin and melatonin biosynthesis
Drugs		CoA-S-trimethylene-acetyl-tryptamine CoA-s-acetyl tryptamine CoA-S-acetyl 5-bromotryptamine Cannabidiol Medical Cannabis Nabiximols
Diseases		Delayed sleep phase syndrome
GWAS		High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494)
Novel Interacting Genes		9 novel interacting genes: BHLHE40 BIRC5 EIF4E3 F2 GRB10 KRTAP8-1 MDFI PRKACA YWHAZ
Interacting Genes		9 interacting genes: BHLHE40 BIRC5 EIF4E3 F2 GRB10 KRTAP8-1 MDFI PRKACA YWHAZ
Entrez ID		15
HPRD ID		02974
Ensembl ID		ENSG00000129673
Uniprot IDs		F1T0I5 Q16613
PDB IDs		6T80
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Survivin Complex Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process ERK1 And ERK2 Cascade Protein Sequestering Activity Protein Domain Specific Binding Negative Regulation Of TORC1 Signaling TORC1 Signaling Regulation Of Macromolecule Metabolic Process Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Insulin Secretion Negative Regulation Of TOR Signaling TOR Signaling Synaptic Target Recognition Regulation Of TORC1 Signaling Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Positive Regulation Of Exit From Mitosis Cobalt Ion Binding Regulation Of Metabolic Process Regulation Of Sequestering Of Calcium Ion Blood Microparticle Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Thrombospondin Receptor Activity Regulation Of Generation Of Precursor Metabolites And Energy Vascular Associated Smooth Muscle Cell Migration Tube Formation Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Protein Localization To Lipid Droplet Interphase Microtubule Organizing Center Regulation Of Gene Expression Neutrophil-mediated Killing Of Gram-negative Bacterium Regulation Of Calcium Ion Transmembrane Transport Positive Regulation Of Protein Secretion Positive Regulation Of Hormone Secretion Golgi Reassembly MRF Binding Regulation Of TOR Signaling Regulation Of Cell Communication Negative Regulation Of DNA-templated Transcription Chromosome Passenger Complex Regulation Of Signaling Negative Regulation Of RNA Biosynthetic Process Regulation Of Protein Localization To Nucleus
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