TTBK2

Description		tau tubulin kinase 2
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Centriole Cytosol Cytoskeleton Cilium Microtubule Cytoskeleton Ciliary Transition Zone Ciliary Basal Body Cell Projection Ciliary Base
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Kinesin Binding Tau Protein Binding Tau-protein Kinase Activity Microtubule Plus-end Binding Protein Serine Kinase Activity
	Biological Process	Microtubule Cytoskeleton Organization Negative Regulation Of Microtubule Depolymerization Signal Transduction Smoothened Signaling Pathway Intracellular Protein Localization Regulation Of Smoothened Signaling Pathway Peptidyl-serine Phosphorylation Cerebellum Development Cerebellar Granular Layer Development Neural Tube Development Cerebellar Granule Cell Precursor Tangential Migration Cell Projection Organization Regulation Of Cell Migration Forebrain Development Protein Localization To Organelle Embryonic Digit Morphogenesis Cilium Assembly Negative Regulation Of Protein Localization To Microtubule Positive Regulation Of Non-motile Cilium Assembly Negative Regulation Of Protein Localization Embryonic Brain Development
Pathways		Anchoring of the basal body to the plasma membrane
Drugs
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Bipolar disorder ( 31043756) Hematocrit ( 32888494) MGMT methylation in smokers ( 26183928)
Novel Interacting Genes		2 novel interacting genes: KLHL12 STARD9
Interacting Genes		2 interacting genes: KLHL12 STARD9
Entrez ID		146057
HPRD ID		10288
Ensembl ID		ENSG00000128881
Uniprot IDs		Q6IQ55 Q8IWY7
PDB IDs		6U0K 6VRF 7O3B 7Q8Y 7Q8Z 7Q90
Enriched GO Terms of Interacting Partners?
Tagcloud ?