CSF2RA

Description		colony stimulating factor 2 receptor subunit alpha
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GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane External Side Of Plasma Membrane Membrane Granulocyte Macrophage Colony-stimulating Factor Receptor Complex Growth Hormone Receptor Complex
	Molecular Function	Cytokine Receptor Activity Growth Hormone Receptor Activity Protein Binding Peptide Hormone Binding Cytokine Binding Signaling Receptor Activity
	Biological Process	Cell Surface Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Growth Hormone Receptor Signaling Pathway Positive Regulation Of Leukocyte Proliferation
Pathways		Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Surfactant metabolism Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4 Interleukin receptor SHC signaling
Drugs		Sargramostim KB002 Regramostim Foreskin fibroblast (neonatal) Foreskin keratinocyte (neonatal) Clove oil
Diseases
GWAS		Mitochondrial heteroplasmy measurement ( 33731350) Schizophrenia ( 17522711)
Novel Interacting Genes		9 novel interacting genes: CHUK CSF2 CSF2RB FATE1 IKBKB KIT LYN PIK3R1 RPSA
Interacting Genes		9 interacting genes: CHUK CSF2 CSF2RB FATE1 IKBKB KIT LYN PIK3R1 RPSA
Entrez ID		1438
HPRD ID		02381
Ensembl ID		ENSG00000198223
Uniprot IDs		P15509
PDB IDs		4NKQ 4RS1
Enriched GO Terms of Interacting Partners?		Cytokine-mediated Signaling Pathway Cytoplasmic Side Of Plasma Membrane Immune System Process Immune Response Response To External Biotic Stimulus Myeloid Leukocyte Differentiation IkappaB Kinase Activity Regulation Of Cytokine Production Positive Regulation Of Leukocyte Proliferation Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway Granulocyte Macrophage Colony-stimulating Factor Receptor Complex Positive Regulation Of Mast Cell Proliferation Fc Receptor Signaling Pathway Interleukin-5-mediated Signaling Pathway Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Scaffold Protein Binding IkappaB Kinase Complex Myeloid Cell Differentiation Histamine Secretion Phosphatidylinositol 3-kinase Activator Activity Regulation Of Mast Cell Proliferation Innate Immune Response Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Leukocyte Proliferation Histamine Transport CD40 Receptor Complex Transferrin Receptor Binding Mononuclear Cell Differentiation Defense Response Defense Response To Symbiont Defense Response To Other Organism Positive Regulation Of DNA-binding Transcription Factor Activity Leukocyte Differentiation Immune Effector Process Immune Response-regulating Signaling Pathway Cellular Response To Cytokine Stimulus Positive Regulation Of Cell Population Proliferation Regulation Of Innate Immune Response Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Regulation Of Immune Response Fc-epsilon Receptor Signaling Pathway Growth Hormone Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Immune System Process Protein Kinase Activity Positive Regulation Of Cytokine Production Innate Immune Response-activating Signaling Pathway Regulation Of DNA-binding Transcription Factor Activity
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