STK35

Description		serine/threonine kinase 35
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Body
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of G2/MI Transition Of Meiotic Cell Cycle
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Adult body size ( 32376654) Basal cell carcinoma ( 33549134) Early spontaneous preterm birth ( 31194736) Immune response to measles-mumps-rubella vaccine ( 24811271) Keratoconus ( 33649486) Plateletcrit ( 32888494) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Novel Interacting Genes		6 novel interacting genes: BMPR1B OSBPL3 PDLIM1 SMAD4 SMURF1 TGFBR1
Interacting Genes		6 interacting genes: BMPR1B OSBPL3 PDLIM1 SMAD4 SMURF1 TGFBR1
Entrez ID		140901
HPRD ID		11612
Ensembl ID		ENSG00000125834
Uniprot IDs		Q8TDR2
PDB IDs
Enriched GO Terms of Interacting Partners?		SMAD Binding I-SMAD Binding Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Transforming Growth Factor Beta Receptor Activity, Type I BMP Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Endothelial Cell Activation Transmembrane Receptor Protein Serine/threonine Kinase Activity Ameboidal-type Cell Migration Regulation Of Extracellular Matrix Assembly Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Extracellular Matrix Organization R-SMAD Binding Cardiac Epithelial To Mesenchymal Transition Cellular Response To BMP Stimulus Activin Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Differentiation Regionalization Ventricular Septum Morphogenesis Neuron Fate Commitment Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of SMAD Protein Signal Transduction Ventricular Cardiac Muscle Tissue Morphogenesis Response To Growth Factor Regulation Of Chondrocyte Differentiation Cardiac Muscle Tissue Morphogenesis Positive Regulation Of Epithelial To Mesenchymal Transition Cellular Response To Transforming Growth Factor Beta Stimulus Pattern Specification Process Regulation Of SMAD Protein Signal Transduction Regulation Of Extracellular Matrix Organization Regulation Of Cell Growth Response To Transforming Growth Factor Beta Regulation Of Cartilage Development Cardiac Septum Morphogenesis Muscle Tissue Morphogenesis Roof Of Mouth Development Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis Engulfment Of Target By Autophagosome Epithelial To Mesenchymal Transition Positive Regulation Of Developmental Process Animal Organ Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Mesenchymal Cell Differentiation
Tagcloud ?