CTCFL

Description		CCCTC-binding factor like
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Nuclear Body
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Histone Binding Chromatin Insulator Sequence Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Protein Localization To Chromosome Epigenetic Regulation Of Gene Expression Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Establishment Of Protein Localization To Chromatin Genomic Imprinting
Pathways
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obesity-related traits ( 23251661) Prudent dietary pattern ( 28644415) Response to cytadine analogues (cytosine arabinoside) ( 24483146) Response to statin therapy ( 20339536) Triglyceride levels ( 32203549) Type 2 diabetes ( 23300278)
Novel Interacting Genes		10 novel interacting genes: AURKA BAG6 BRCA1 H1-1 H2AC20 H3C1 PRMT7 SP1 TBP ZDHHC17
Interacting Genes		10 interacting genes: AURKA BAG6 BRCA1 H1-1 H2AC20 H3C1 PRMT7 SP1 TBP ZDHHC17
Entrez ID		140690
HPRD ID		09512
Ensembl ID		ENSG00000124092
Uniprot IDs		A6XGM0 A6XGM9 Q8NI51 V9GY73 V9GYX4
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromatin Remodeling Euchromatin Pronucleus Epigenetic Regulation Of Gene Expression Structural Constituent Of Chromatin Nucleosome Nucleoplasm Regulation Of Macromolecule Metabolic Process Protein-DNA Complex Assembly Transcription Cis-regulatory Region Binding Centrosome Cycle Regulation Of Centrosome Cycle DNA Binding Chromosome Regulation Of Metabolic Process Male Germ Cell Nucleus Positive Regulation Of Hydrogen Sulfide Biosynthetic Process Cellular Response To Wortmannin Perforant Pathway To Dendrate Granule Cell Synapse Ubiquitin Protein Ligase Binding Histone H2AK127 Ubiquitin Ligase Activity Nucleus Microtubule Organizing Center Organization Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Programmed Cell Death Cellular Component Assembly Chromosome Organization Response To Wortmannin Protein Heterodimerization Activity Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Protein Modification Process Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Oocyte Maturation BAT3 Complex Protein-arginine Omega-N Symmetric Methyltransferase Activity Nucleosome Assembly BRCA1-B Complex Regulation Of Cell Cycle G2/M Phase Transition Male Gamete Generation Spermatogenesis Spindle Assembly Involved In Female Meiosis I Germinal Vesicle Positive Regulation Of Proteasomal Protein Catabolic Process Histone H3S10 Kinase Activity TFIIB-class Transcription Factor Binding
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