IL31RA

Description		interleukin 31 receptor A
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane Axon Presynaptic Membrane Cell Projection Receptor Complex Synapse
	Molecular Function	Transcription Coactivator Activity Cytokine Receptor Activity Protein Kinase Binding Cytokine Binding
	Biological Process	MAPK Cascade Glandular Epithelial Cell Differentiation Immune System Process Acute Inflammatory Response To Antigenic Stimulus Defense Response Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Cell Differentiation Monocyte Differentiation Macrophage Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Homeostatic Process Negative Regulation Of Macrophage Activation Negative Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Cell Surface Receptor Signaling Pathway Via STAT Defense Response To Other Organism
Pathways		IL-6-type cytokine receptor ligand interactions
Drugs
Diseases
GWAS		Crohn's disease ( 23128233)
Novel Interacting Genes		2 novel interacting genes: IL6ST LIFR
Interacting Genes		2 interacting genes: IL6ST LIFR
Entrez ID		133396
HPRD ID		17145
Ensembl ID		ENSG00000164509
Uniprot IDs		B4DNJ2 Q8NI17
PDB IDs
Enriched GO Terms of Interacting Partners?		Leukemia Inhibitory Factor Receptor Activity Ciliary Neurotrophic Factor Receptor Activity Leukemia Inhibitory Factor Signaling Pathway Oncostatin-M Receptor Activity Oncostatin-M-mediated Signaling Pathway Ciliary Neurotrophic Factor-mediated Signaling Pathway Ciliary Neurotrophic Factor Receptor Binding Cytokine Binding Growth Factor Binding Cytokine Receptor Activity Receptor Complex Interleukin-27 Receptor Activity Interleukin-6 Binding Interleukin-6 Receptor Activity Oncostatin-M Receptor Complex Interleukin-6 Receptor Complex Ciliary Neurotrophic Factor Receptor Complex External Side Of Plasma Membrane Interleukin-11 Receptor Activity Interleukin-11 Binding Cytokine-mediated Signaling Pathway Negative Regulation Of Interleukin-6-mediated Signaling Pathway Interleukin-11-mediated Signaling Pathway Interleukin-6 Receptor Binding Interleukin-27-mediated Signaling Pathway Response To Peptide Response To Cytokine Intestinal Epithelial Cell Development Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Platelet Aggregation Positive Regulation Of Astrocyte Differentiation T-helper 17 Cell Lineage Commitment Columnar/cuboidal Epithelial Cell Development Protein Tyrosine Kinase Activator Activity Interleukin-6-mediated Signaling Pathway T-helper Cell Lineage Commitment Positive Regulation Of Homotypic Cell-cell Adhesion CD4-positive, Alpha-beta T Cell Lineage Commitment Alpha-beta T Cell Lineage Commitment CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment Positive Regulation Of Cell Population Proliferation Positive Regulation Of Acute Inflammatory Response Regulation Of Astrocyte Differentiation Positive Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Platelet Aggregation T Cell Lineage Commitment Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Glial Cell Differentiation Positive Regulation Of Notch Signaling Pathway Regulation Of Acute Inflammatory Response
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