SETD9

Description		SET domain containing 9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion
	Molecular Function	Protein Binding Methyltransferase Activity Lysine N-methyltransferase Activity Transferase Activity
	Biological Process	Methylation Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Regulation of TP53 Activity through Methylation
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Novel Interacting Genes		3 novel interacting genes: ANKRD55 CRK PLCG2
Interacting Genes		3 interacting genes: ANKRD55 CRK PLCG2
Entrez ID		133383
HPRD ID		14572
Ensembl ID		ENSG00000155542
Uniprot IDs		Q8NE22
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Yeast Phosphotyrosine Residue Binding Protein Tyrosine Kinase Binding Response To Fungus Scaffold Protein Binding Helper T Cell Diapedesis Protein Phosphorylated Amino Acid Binding Response To Cholecystokinin Cerebellar Neuron Development Inositol Trisphosphate Biosynthetic Process Follicular B Cell Differentiation Response To Hepatocyte Growth Factor Positive Regulation Of Locomotion Regulation Of Innate Immune Response Cellular Response To Nitric Oxide Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Cell Migration Positive Regulation Of Rac Protein Signal Transduction Diapedesis Positive Regulation Of MAPK Cascade Positive Regulation Of Cell Motility Positive Regulation Of Receptor Clustering Regulation Of Receptor Clustering Insulin-like Growth Factor Receptor Binding Cellular Response To Insulin-like Growth Factor Stimulus Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Reelin-mediated Signaling Pathway Cellular Response To Reactive Nitrogen Species Response To Nitric Oxide Response To Endothelin Cellular Response To Endothelin Postsynaptic Specialization Assembly Positive Regulation Of Neuroinflammatory Response Regulation Of Dendritic Cell Cytokine Production Intracellular Vesicle Positive Regulation Of Interleukin-23 Production Macrophage Activation Involved In Immune Response Cellular Response To Lectin Antifungal Innate Immune Response Stimulatory C-type Lectin Receptor Signaling Pathway Regulation Of Interleukin-23 Production Phospholipase C Activity Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Inositol Trisphosphate Metabolic Process Positive Regulation Of Dendritic Cell Cytokine Production Inositol Phosphate Biosynthetic Process Positive Regulation Of Phagocytosis, Engulfment Phosphorylation-dependent Protein Binding Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Postsynaptic Specialization Organization
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