SCLT1

Description		sodium channel and clathrin linker 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Microtubule Cytoskeleton Ciliary Basal Body Clathrin Complex Ciliary Transition Fiber
	Molecular Function	Protein Binding Sodium Channel Regulator Activity Clathrin Binding
	Biological Process	Clustering Of Voltage-gated Sodium Channels Cilium Assembly
Pathways		Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease (moderate to severe) ( 24621683) Metabolite levels ( 23823483) Problematic alcohol use in trauma-exposed individuals ( 29082582) Triglyceride levels x loop diuretics use interaction ( 31806883)
Novel Interacting Genes		5 novel interacting genes: CALM1 IKBKG LNX1 MAPK8IP2 SCN10A
Interacting Genes		5 interacting genes: CALM1 IKBKG LNX1 MAPK8IP2 SCN10A
Entrez ID		132320
HPRD ID		08700
Ensembl ID		ENSG00000151466
Uniprot IDs		A0A494C0G8 D6RBA6 Q96NL6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Heart Contraction Transmembrane Transporter Binding Regulation Of Muscle Contraction Mitochondrion-endoplasmic Reticulum Membrane Tethering Positive Regulation Of Sequestering Of Calcium Ion Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Intracellular Signaling Cassette Adenylate Cyclase Activator Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Membrane Potential Autophagosome Membrane Docking Protein-containing Complex Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Muscle System Process Regulation Of Cardiac Muscle Contraction Regulation Of System Process Spindle Pole Regulation Of Heart Rate Regulation Of Striated Muscle Contraction AV Node Cell Action Potential Bundle Of His Cell Action Potential Negative Regulation Of Apoptotic Signaling Pathway Linear Polyubiquitin Binding IkappaB Kinase Complex Nonassociative Learning Regulation Of Blood Circulation Negative Regulation Of Voltage-gated Calcium Channel Activity Clathrin Complex Signal Complex Assembly Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Regulation Of Monoatomic Ion Transmembrane Transport Voltage-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Transferrin Receptor Binding JUN Kinase Binding Voltage-gated Sodium Channel Complex Anoikis MAP-kinase Scaffold Activity Titin Binding Calcium Channel Inhibitor Activity Regulation Of Voltage-gated Calcium Channel Activity Detection Of Calcium Ion Protein Phosphatase Activator Activity Regulation Of Cell Communication By Electrical Coupling Calyx Of Held Regulation Of Monoatomic Ion Transport
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