ADK

Description		adenosine kinase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Nucleotide Binding RNA Binding Adenosine Kinase Activity Deoxyadenosine Kinase Activity ATP Binding Kinase Activity Transferase Activity Metal Ion Binding
	Biological Process	Purine Nucleobase Metabolic Process Purine Ribonucleoside Salvage DATP Biosynthetic Process Ribonucleoside Monophosphate Biosynthetic Process GMP Salvage AMP Salvage DAMP Salvage
Pathways		Purine salvage Ribavirin ADME
Drugs		Adenosine phosphate 7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE 5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE
Diseases
GWAS		Adult body size ( 32376654) Cardiac troponin-I levels ( 31014085) Diverticular disease ( 30177863) Drug experimentation measurement ( 30718321) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hypospadias ( 25108383) Lymphocyte count ( 32888494) Permanent tooth development ( 21931568) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Refractive error ( 32231278) Soluble interleukin-2 receptor subunit alpha ( 26293465) Systolic blood pressure ( 30578418)
Novel Interacting Genes		3 novel interacting genes: FICD PLEKHA5 SRD5A3
Interacting Genes		3 interacting genes: FICD PLEKHA5 SRD5A3
Entrez ID		132
HPRD ID		00039
Ensembl ID		ENSG00000156110
Uniprot IDs		A0A140VJE0 A0A5F9ZH31 A0A5F9ZH72 A0A5F9ZHJ1 P55263
PDB IDs		1BX4 2I6A 2I6B 4O1L
Enriched GO Terms of Interacting Partners?		Protein Adenylylhydrolase Activity AMPylase Activity Protein Adenylylation Protein Deadenylylation Polyprenol Reductase Activity Polyprenal Reductase Activity 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP+) Activity 3-oxo-5-alpha-steroid 4-dehydrogenase Activity Polyprenol Catabolic Process Dolichyl Monophosphate Biosynthetic Process Dolichyl Diphosphate Biosynthetic Process Oxidoreductase Activity, Acting On The CH-CH Group Of Donors, NAD Or NADP As Acceptor Androgen Biosynthetic Process Negative Regulation Of GTPase Activity Regulation Of IRE1-mediated Unfolded Protein Response Dolichol-linked Oligosaccharide Biosynthetic Process Phosphatidylinositol-5-phosphate Binding Reproductive System Development Oxidoreductase Activity, Acting On The CH-CH Group Of Donors Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding Androgen Metabolic Process Steroid Hormone Biosynthetic Process Alcohol Catabolic Process Negative Regulation Of Hydrolase Activity Regulation Of Endoplasmic Reticulum Unfolded Protein Response Hormone Biosynthetic Process Phosphatidylinositol-3-phosphate Binding Hsp70 Protein Binding Endoplasmic Reticulum Membrane Response To Unfolded Protein Steroid Biosynthetic Process Regulation Of Response To Endoplasmic Reticulum Stress Protein-folding Chaperone Binding Nucleotidyltransferase Activity Isoprenoid Metabolic Process
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