COL13A1

Description		collagen type XIII alpha 1 chain
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Collagen Type XIII Trimer Basement Membrane Endoplasmic Reticulum Lumen Plasma Membrane Membrane Extracellular Matrix Synapse Postsynaptic Membrane
	Molecular Function	Protein Binding Heparin Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Ossification Morphogenesis Of A Branching Structure Endochondral Ossification Cell Adhesion Cell-matrix Adhesion Cell Differentiation Cell-cell Adhesion
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Integrin cell surface interactions Collagen chain trimerization
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Antidepressant treatment resistance (number of drugs prescribed) ( 30700811) Carboplatin disposition in epthelial ovarian cancer ( 29367611) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Early childhood aggressive behavior ( 26087016) Middle childhood and early adolescence aggressive behavior ( 26087016) Non-alcoholic fatty liver disease histology (lobular) ( 20708005) Optic disc size ( 31809533) Parkinson's disease ( 23793441) PR interval ( 32439900) Response to fenofibrate (total cholesterol levels) ( 27002377) Triglyceride levels in HIV infection ( 33109212) Ulcerative colitis ( 25082827) Upper eyelid morphology ( 29921221)
Novel Interacting Genes		7 novel interacting genes: FN1 HSPG2 ITGA1 MTDH NID1 NID2 SPARC
Interacting Genes		7 interacting genes: FN1 HSPG2 ITGA1 MTDH NID1 NID2 SPARC
Entrez ID		1305
HPRD ID		00383
Ensembl ID		ENSG00000197467
Uniprot IDs		A0A2R8YGI3 A0A669KB16 A0A669KB28 A0A6E1W314 Q5TAT6
PDB IDs
Enriched GO Terms of Interacting Partners?		Collagen Binding Basement Membrane Cell-matrix Adhesion Extracellular Matrix Structural Constituent Extracellular Matrix Cell-substrate Adhesion Proteoglycan Binding Calcium Ion Binding Extracellular Matrix Binding Basement Membrane Organization Regulation Of Anatomical Structure Morphogenesis Cell Adhesion Regulation Of Vasculature Development Regulation Of Angiogenesis Platelet Alpha Granule Lumen Extracellular Exosome Extracellular Region Integrin-mediated Signaling Pathway Collagen V Binding Integrin Alpha1-beta1 Complex Regulation Of Developmental Process Negative Regulation Of Monocyte Activation Regulation Of Multicellular Organismal Development Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Negative Regulation Of Vasculature Development Negative Regulation Of Angiogenesis Calcium-independent Cell-matrix Adhesion Integrin Binding Extracellular Space Regulation Of Endothelial Cell Proliferation Positive Regulation Of Signal Transduction Collagen Binding Involved In Cell-matrix Adhesion Regulation Of Cell Population Proliferation Neural Crest Cell Migration Involved In Autonomic Nervous System Development Negative Regulation Of Cell Population Proliferation Phosphatase Activator Activity Intercellular Canaliculus Positive Regulation Of Cell Communication Regulation Of Cell Adhesion Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Signaling Fibrinogen Complex Regulation Of Cell-substrate Adhesion Regulation Of Basement Membrane Organization Laminin-1 Binding Semicircular Canal Morphogenesis Peptidase Activator Activity Blood Coagulation, Fibrin Clot Formation Protein Complex Involved In Cell-matrix Adhesion
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