AP1S3

Description		adaptor related protein complex 1 subunit sigma 3
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GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Early Endosome Golgi Apparatus Cytosol Clathrin-coated Pit Membrane Membrane Coat AP-1 Adaptor Complex Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Clathrin Adaptor Activity
	Biological Process	Protein Targeting Intracellular Protein Transport Protein Transport Vesicle-mediated Transport Platelet Dense Granule Organization Melanosome Assembly
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Airway wall thickness ( 25517131) Asthma ( 30929738 32296059) Asthma (childhood onset) ( 30929738) Initial alcohol sensitivity ( 30276832) Night sleep phenotypes ( 27126917) Sodium levels ( 29403010)
Novel Interacting Genes		1 novel interacting genes: PRKAG1
Interacting Genes		1 interacting genes: PRKAG1
Entrez ID		130340
HPRD ID		16495
Ensembl ID		ENSG00000152056
Uniprot IDs		Q96PC3
PDB IDs		4HMY 6CM9 6CRI 6D83 6D84 6DFF 7R4H 7UX3 8D4C 8D4D 8D4E 8D4F 8D4G 8D9R 8D9S 8D9T 8D9U 8D9V 8D9W
Enriched GO Terms of Interacting Partners?		CAMP-dependent Protein Kinase Regulator Activity CAMP-dependent Protein Kinase Activity AMP-activated Protein Kinase Activity Regulation Of Carbon Utilization Nucleotide-activated Protein Kinase Complex AMP Binding Protein Kinase Regulator Activity Positive Regulation Of Gluconeogenesis Positive Regulation Of Glucose Metabolic Process Cellular Response To Glucose Starvation Regulation Of Gluconeogenesis Regulation Of Response To Nutrient Levels Regulation Of Glycolytic Process ADP Binding Regulation Of Carbohydrate Catabolic Process Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Regulation Of Glucose Metabolic Process Fatty Acid Biosynthetic Process Import Into Nucleus Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Small Molecule Metabolic Process Cellular Response To Starvation Nuclear Transport Nucleocytoplasmic Transport Response To Starvation Cellular Response To Nutrient Levels Carboxylic Acid Biosynthetic Process Fatty Acid Metabolic Process
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