COL4A6

Description		collagen type IV alpha 6 chain
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Collagen Type IV Trimer Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Cell Adhesion Extracellular Matrix Organization Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Cellular Response To Amino Acid Stimulus
Pathways		Collagen degradation Collagen degradation Fibronectin matrix formation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Integrin cell surface interactions Anchoring fibril formation Crosslinking of collagen fibrils Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans Collagen chain trimerization Attachment of bacteria to epithelial cells
Drugs
Diseases
GWAS		Electrodermal activity ( 25387706)
Novel Interacting Genes		12 novel interacting genes: APP CD93 DCN FBLN2 FN1 HABP2 MAGEA6 MATN2 MMP9 NOTCH1 OSM SERPINE2
Interacting Genes		12 interacting genes: APP CD93 DCN FBLN2 FN1 HABP2 MAGEA6 MATN2 MMP9 NOTCH1 OSM SERPINE2
Entrez ID		1288
HPRD ID		02364
Ensembl ID		ENSG00000197565
Uniprot IDs		A0A087WZY5 A8MXH5 A8VPY0 B2RTX6 B7ZMM7 F5H3Q5 Q14031
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Region Extracellular Matrix Glycosaminoglycan Binding Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Peptidase Activator Activity Extracellular Space Regulation Of Cell Migration Regulation Of Locomotion Regulation Of Cell Motility Calcium Ion Binding Regulation Of Development, Heterochronic Positive Regulation Of Astrocyte Differentiation Regulation Of Timing Of Cell Differentiation Positive Regulation Of Cell Communication Positive Regulation Of Signaling Extracellular Matrix Structural Constituent Platelet Alpha Granule Signaling Receptor Binding Regulation Of Intracellular Signal Transduction Heparin Binding Negative Regulation Of Transport Extracellular Matrix Binding Regulation Of Astrocyte Differentiation Negative Regulation Of Signaling Negative Regulation Of Cell Communication Endodermal Cell Differentiation Regulation Of Cell Differentiation Positive Regulation Of Glial Cell Differentiation Amyloid-beta Complex Regulation Of Phosphorus Metabolic Process Growth Cone Lamellipodium Regulation Of Growth Regulation Of Developmental Process Regulation Of Response To Calcium Ion Regulation Of Cell Population Proliferation Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Extracellular Matrix Organization Positive Regulation Of Signal Transduction Dendrite Development Extracellular Structure Organization Regulation Of Cell-substrate Adhesion Positive Regulation Of Neurogenesis Response To Wounding Negative Regulation Of Epithelial Cell Differentiation
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