UHMK1

Description		U2AF homology motif kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Axon Dendrite Cytoplasm Neuronal Ribonucleoprotein Granule
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Ribonucleoprotein Complex Binding Protein Serine Kinase Activity
	Biological Process	Peptidyl-serine Phosphorylation Neuron Projection Development Positive Regulation Of Translational Initiation Regulation Of Protein Export From Nucleus Regulation Of Cell Cycle
Pathways		Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Drugs
Diseases
GWAS		Bone mineral density (femoral neck) ( 27424934) Bone mineral density (total hip) ( 27424934) Discordance in emotional problems in monozygotic twins ( 27043157) Takayasu arteritis ( 25604533)
Novel Interacting Genes		9 novel interacting genes: AIRIM DEPDC1B LMO1 NDUFAF3 PAM RGS8 STMN1 TMSB4X TSGA10IP
Interacting Genes		9 interacting genes: AIRIM DEPDC1B LMO1 NDUFAF3 PAM RGS8 STMN1 TMSB4X TSGA10IP
Entrez ID		127933
HPRD ID		12318
Ensembl ID		ENSG00000152332
Uniprot IDs		Q8TAS1
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidylamidoglycolate Lyase Activity Peptidylglycine Monooxygenase Activity Fatty Acid Primary Amide Biosynthetic Process Actin Monomer Sequestering Activity Peptide Amidation Positive Regulation Of Proton-transporting ATP Synthase Activity, Rotational Mechanism Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Supramolecular Fiber Organization Regulation Of GTPase Activity Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity Regulation Of Catalytic Activity Negative Regulation Of Protein-containing Complex Assembly Regulation Of T Cell Homeostatic Proliferation Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Ascorbate As One Donor, And Incorporation Of One Atom Of Oxygen Positive Regulation Of Ligase Activity Negative Regulation Of Hematopoietic Stem Cell Differentiation
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