LTB4R

Description		leukotriene B4 receptor
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GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding Leukotriene B4 Receptor Activity G Protein-coupled Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Muscle Contraction Inflammatory Response Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Leukotriene Signaling Pathway
Pathways		Leukotriene receptors G alpha (q) signalling events
Drugs		Amelubant Morniflumate Leukotriene B4
Diseases
GWAS		Parent of origin effect on language impairment (paternal) ( 24571439)
Novel Interacting Genes		5 novel interacting genes: GNA15 GNAI2 GRK6 TNFSF4 YWHAG
Interacting Genes		5 interacting genes: GNA15 GNAI2 GRK6 TNFSF4 YWHAG
Entrez ID		1241
HPRD ID		03320
Ensembl ID		ENSG00000213903
Uniprot IDs		Q15722
PDB IDs		7K15 7VKT
Enriched GO Terms of Interacting Partners?		G Protein-coupled Acetylcholine Receptor Signaling Pathway Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Complex Acetylcholine Receptor Signaling Pathway Postsynaptic Signal Transduction G Protein-coupled Receptor Binding Positive Regulation Of T Cell Mediated Immunity Negative Regulation Of Adaptive Immune Response Positive Regulation Of Interleukin-4-dependent Isotype Switching To IgE Isotypes Positive Regulation Of CD4-positive, Alpha-beta T Cell Costimulation T-helper 2 Cell Activation Response To Nitrogen Dioxide Regulation Of T Cell Mediated Immunity Memory T Cell Activation Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Positive Regulation Of T Cell Costimulation Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Adaptive Immune Response Negative Regulation Of T Cell Activation G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Catalytic Activity Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Leukocyte Cell-cell Adhesion Defense Response To Nematode Protein Kinase C Inhibitor Activity Signal Transduction Negative Regulation Of Lymphocyte Activation Beta-adrenergic Receptor Kinase Activity Negative Regulation Of T-helper 1 Cell Differentiation Positive Regulation Of Isotype Switching To IgE Isotypes Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Negative Regulation Of Cell-cell Adhesion Negative Regulation Of Leukocyte Activation Regulation Of Lymphocyte Mediated Immunity Negative Regulation Of Immune Response Regulation Of Adaptive Immune Response Negative Regulation Of Cell Activation Negative Regulation Of Regulatory T Cell Differentiation G Protein-coupled Receptor Kinase Activity Positive Regulation Of T-helper 2 Cell Differentiation Tumor Necrosis Factor Receptor Superfamily Binding Positive Regulation Of T Cell Activation Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway Negative Regulation Of Calcium Ion-dependent Exocytosis G Protein-coupled Adenosine Receptor Signaling Pathway Positive Regulation Of Immune Effector Process Positive Regulation Of Memory T Cell Differentiation Positive Regulation Of Leukocyte Cell-cell Adhesion
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