CLPTM1

Description		CLPTM1 regulator of GABA type A receptor forward trafficking
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Endomembrane System Membrane
	Molecular Function	Protein Binding GABA Receptor Binding
	Biological Process	Cell Differentiation Regulation Of T Cell Differentiation In Thymus
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Apolipoprotein B levels ( 32203549) Basal cell carcinoma ( 31174203) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Carotid intima media thickness (maximum) ( 31801372) Carotid intima media thickness (mean) ( 31801372) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Cerebrospinal fluid AB1-42 levels ( 29274321) Cerebrospinal fluid p-tau levels ( 29274321) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid t-tau levels ( 29274321) Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321) Hippocampal volume ( 29274321) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Keratinocyte cancer (MTAG) ( 31174203) LDL cholesterol levels ( 32203549) Logical memory (delayed recall) ( 29274321) Logical memory (immediate recall) ( 29274321) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Novel Interacting Genes		8 novel interacting genes: CCR2 CCR4 F2RL1 FZD7 LINC00839 SLC22A1 SLC22A2 UNC93B1
Interacting Genes		8 interacting genes: CCR2 CCR4 F2RL1 FZD7 LINC00839 SLC22A1 SLC22A2 UNC93B1
Entrez ID		1209
HPRD ID		07544
Ensembl ID		ENSG00000104853
Uniprot IDs		A0A0S2Z3H2 O96005
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Transport Pyrimidine Nucleoside Transmembrane Transporter Activity Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Polyamine Transmembrane Transport Serotonin Uptake Norepinephrine Transport Prostaglandin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Catecholamine Uptake Dopamine Uptake Azole Transmembrane Transport Serotonin Transport G Protein-coupled Receptor Activity Quaternary Ammonium Group Transport Prostaglandin Transport Pyrimidine-containing Compound Transmembrane Transport Neurotransmitter Transmembrane Transporter Activity Vitamin Transmembrane Transport Organic Anion Transmembrane Transporter Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Dopamine Transport Neurotransmitter Reuptake Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Xenobiotic Transmembrane Transporter Activity Monoamine Transport Neurotransmitter Uptake Purine-containing Compound Transmembrane Transport Vitamin Transport Xenobiotic Transport Vascular Process In Circulatory System G Protein-coupled Receptor Signaling Pathway Circulatory System Process Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream
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