COMTD1

Description		catechol-O-methyltransferase domain containing 1
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GO Annotations	Cellular Component	Mitochondrion Membrane
	Molecular Function	Protein Binding Methyltransferase Activity O-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Transferase Activity
	Biological Process	Methylation
Pathways
Drugs		S-adenosyl-L-homocysteine Sinapoyl coenzyme A Feruloyl Coenzyme A
Diseases
GWAS		Breast size ( 22747683) Lung function (FVC) ( 30061609)
Novel Interacting Genes		4 novel interacting genes: PAXIP1 UBQLN1 UPF2 USP54
Interacting Genes		4 interacting genes: PAXIP1 UBQLN1 UPF2 USP54
Entrez ID		118881
HPRD ID		08678
Ensembl ID		ENSG00000165644
Uniprot IDs		Q86VU5
PDB IDs		2AVD
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Ubiquitination Negative Regulation Of Store-operated Calcium Channel Activity Regulation Of Protein Ubiquitination Chorion Development Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Post-translational Protein Modification
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